For Debate: Combination Growth Hormone and Insulin-Like Growth Factor-I Therapy for Childhood Growth Disorders: Prime Time or Too Much Dime?

4区医学 Q2 Medicine

Pediatric endocrinology reviews : PER Pub Date : 2018-03-01 DOI:10.17458/per.vol15.2018.g.fd.combinationgrowhhormoneandinsuline

Mitchell E Geffner

引用次数: 1

Abstract

Although metabolic outcomes may be aided by dual therapy with GI and IGF-I, the one published study of the combination approach to treat children with non-GH-deficient short stature showed only a meager additional height response compared to that achieved with GH alone.

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辩论:生长激素和胰岛素样生长因子- 1联合治疗儿童生长障碍:黄金时间还是太多钱?

虽然GI和IGF-I的双重治疗可能有助于代谢结果，但一项已发表的联合治疗非GH缺乏性矮小儿童的研究表明，与单独使用GH相比，仅能获得微不足道的额外身高反应。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Pediatric endocrinology reviews : PER Medicine-Endocrinology, Diabetes and Metabolism

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期刊介绍： PEDIATRIC ENDOCRINOLOGY REVIEWS (PER) publishes scholarly review articles in all areas of clinical and experimental Endocrinology, Diabetes, Nutrition and Metabolism. PER is intended for practicing pediatricians, pediatric endocrinologists, pediatric diabetologists, pediatric gastroenterologists, neonatologists, pediatric gynecologists, nutritionists, sport physicians and pediatricians-in-training. PER will also publish topics on specific subjects or as proceedings of scientific meetings in the above fields of interest. All articles, whether invited or direct contributions, are peer-reviewed. PER publishes correspondence, book reviews, a meeting calendar and meeting reports.