More Evidence for the Therapeutic Role of Pramipexole in Upper Limb Restlessness Due to Cervical Disc Pathology?

IF 3.2 Q2 Pharmacology, Toxicology and Pharmaceutics

Current clinical pharmacology Pub Date : 2018-01-01 DOI:10.2174/1574884713666180227165917

Burak Yulug, Lutfu Hanoglu, Sema Brandmeier

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引用次数: 0

Abstract

Background: The causal link between upper limb restlessness and cervical disc prolapsus is still unclear, and the exact role of the spinal cord in the origination of limb restlessness is not yet completely understood.

Methods: Here we have evaluated the therapeutic effect of pramipexole (0.5 mg/kg) in a 47-year old male with cervical disc prolapsus who described restlessness in his upper limb and neck.

Results: The patient felt significantly better, and his symptoms improved near to complete after five days when we initiated 0.5 mg/day pramipexole treatment.

Conclusion: In our present paper, we provide more evidence for the role of pramipexole (0.5 mg/day) in limb restlessness which is associated with cervical disc herniation. In this context, we also have discussed the underlying pathophysiology which seems to be responsible for the restlessness symptoms of the patients.

查看原文本刊更多论文

普拉克索治疗颈椎间盘病理所致上肢躁动的更多证据?

背景:上肢躁动与颈椎间盘突出之间的因果关系尚不清楚，脊髓在肢体躁动起源中的确切作用尚未完全了解。方法:我们评估了普拉克索(0.5 mg/kg)治疗47岁男性颈椎间盘突出症患者上肢和颈部躁动的疗效。结果:患者感觉明显好转，开始0.5 mg/d丙哌索治疗5天后症状接近完全改善。结论:在本文中，我们为普拉克索(0.5 mg/d)在与颈椎间盘突出症相关的肢体不安中的作用提供了更多的证据。在这种情况下，我们也讨论了潜在的病理生理，这似乎是负责躁动症状的患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current clinical pharmacology PHARMACOLOGY & PHARMACY-

CiteScore

3.60

自引率

0.00%

发文量

期刊介绍： Current Clinical Pharmacology publishes frontier reviews on all the latest advances in clinical pharmacology. The journal"s aim is to publish the highest quality review articles in the field. Topics covered include: pharmacokinetics; therapeutic trials; adverse drug reactions; drug interactions; drug metabolism; pharmacoepidemiology; and drug development. The journal is essential reading for all researchers in clinical pharmacology.