Oral Health: The Need for Both Conventional Microbial and Molecular Characterization.

Q2 Biochemistry, Genetics and Molecular Biology
High-Throughput Pub Date : 2017-08-01 DOI:10.3390/ht6030011
Elisheva Friedman, Negin Alizadeh, Zvi Loewy
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引用次数: 7

Abstract

This study aims to consider the microbial distribution in oral disease, as well as gene analysis and expression, in elucidating: 1, the fundamental underpinnings of oral disease, and 2, the potential relationship between oral diseases and systemic health. A key focus is identifying the microbiota associated with oral disease manifestations characterized by both conventional microbiological and molecular methods. Variations in the observed microbial populations characterized by conventional and molecular approaches have been identified for caries, periodontitis, peri-implantitis, and stomatitis. The discovery of therapeutic approaches for oral disease will require comprehensive microbial and genomic analysis. This study evaluated the current state of the relevant microbial and genomic information for several prevalent oral diseases.

口腔健康:对传统微生物和分子表征的需求。
本研究旨在研究口腔疾病中的微生物分布、基因分析和表达,以阐明:1、口腔疾病的基本基础;2、口腔疾病与全身健康之间的潜在关系。一个关键的重点是确定与口腔疾病表现相关的微生物群,这些微生物群以传统的微生物学和分子方法为特征。通过传统方法和分子方法观察到的微生物种群的变化已经被确定为龋齿、牙周炎、种植周炎和口炎。发现治疗口腔疾病的方法需要全面的微生物和基因组分析。本研究评估了几种流行口腔疾病的相关微生物和基因组信息的现状。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
High-Throughput
High-Throughput Biochemistry, Genetics and Molecular Biology-Biotechnology
CiteScore
3.60
自引率
0.00%
发文量
0
审稿时长
9 weeks
期刊介绍: High-Throughput (formerly Microarrays, ISSN 2076-3905) is a multidisciplinary peer-reviewed scientific journal that provides an advanced forum for the publication of studies reporting high-dimensional approaches and developments in Life Sciences, Chemistry and related fields. Our aim is to encourage scientists to publish their experimental and theoretical results based on high-throughput techniques as well as computational and statistical tools for data analysis and interpretation. The full experimental or methodological details must be provided so that the results can be reproduced. There is no restriction on the length of the papers. High-Throughput invites submissions covering several topics, including, but not limited to: -Microarrays -DNA Sequencing -RNA Sequencing -Protein Identification and Quantification -Cell-based Approaches -Omics Technologies -Imaging -Bioinformatics -Computational Biology/Chemistry -Statistics -Integrative Omics -Drug Discovery and Development -Microfluidics -Lab-on-a-chip -Data Mining -Databases -Multiplex Assays
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