Bacterial Conjunctivitis in Childhood: Etiology, Clinical Manifestations, Diagnosis, and Management.

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics
Alexander K C Leung, Kam L Hon, Alex H C Wong, Andrew S Wong
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引用次数: 16

Abstract

Background: Bacterial conjunctivitis is a common reason for children to be seen in pediatric practices. A correct diagnosis is important so that appropriate treatment can be instituted.

Objective: To provide an update on the evaluation, diagnosis, and treatment of bacterial conjunctivitis in children.

Methods: A PubMed search was completed in Clinical Queries using the key term "bacterial conjunctivitis". Patents were searched using the key term "bacterial conjunctivitis" from www.freepatentsonline.com and www.google.com/patents.

Results: In the neonatal period, bacterial conjunctivitis is rare and the most common cause of organism is Staphylococcus aureus, followed by Chlamydia trachomatis. In infants and older children, bacterial conjunctivitis is most often caused by Haemophilus influenzae, Streptococcus pneumoniae, and Moraxella catarrhalis. Clinically, bacterial conjunctivitis is characterized by a purulent eye discharge, or sticky eyes on awakening, a foreign body sensation and conjunctival injection (pink eye). The diagnosis is made clinically. Cultures are unnecessary. Some authors suggest a watchful observation approach as most cases of bacterial conjunctivitis are self-limited. A Cochrane review suggests the use of antibiotic eye drops is associated with modestly improved rates of clinical and microbiological remission as compared to the use of placebo. Various investigators have also disclosed patents for the treatment of conjunctivitis.

Conclusion: The present consensus supports the use of topical antibiotics for bacterial conjunctivitis. Topical antibiotics shorten the course of the disease, reduce discomfort, prevent person-to-person transmission and reduce the rate of reinfection.

儿童期细菌性结膜炎:病因、临床表现、诊断和治疗。
背景:细菌性结膜炎是儿童就诊的常见原因。正确的诊断对于制定适当的治疗是很重要的。目的:提供儿童细菌性结膜炎的评价、诊断和治疗的最新进展。方法:在临床查询中使用关键词“细菌性结膜炎”完成PubMed检索。以“细菌性结膜炎”为关键词从www.freepatentsonline.com和www.google.com/patents.Results:检索专利。在新生儿期,细菌性结膜炎比较少见,最常见的病原菌是金黄色葡萄球菌,其次是沙眼衣原体。在婴儿和年龄较大的儿童中,细菌性结膜炎最常由流感嗜血杆菌、肺炎链球菌和卡他莫拉菌引起。细菌性结膜炎的临床特征是眼脓性分泌物,或醒来时眼黏,有异物感和结膜注射(红眼)。临床诊断。文化是不必要的。一些作者建议警惕观察,因为大多数细菌性结膜炎是自限性的。一项Cochrane综述显示,与使用安慰剂相比,抗生素滴眼液与临床和微生物缓解率的适度改善有关。许多研究者也公开了治疗结膜炎的专利。结论:目前的共识支持使用外用抗生素治疗细菌性结膜炎。局部抗生素缩短病程,减少不适,防止人与人之间的传播,并降低再感染率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
期刊介绍: Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.
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