Risk factors for acute kidney injury after orthotopic liver transplantation: A single-center data analysis.

Q Engineering

Journal of Huazhong University of Science and Technology [Medical Sciences] Pub Date : 2017-12-01 Epub Date: 2017-12-21 DOI:10.1007/s11596-017-1818-5

Zhi-Qiang Zhou, Long-Chang Fan, Xu Zhao, Wei Xia, Ai-Lin Luo, Yu-Ke Tian, Xue-Ren Wang

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引用次数: 7

Abstract

Acute kidney injury (AKI) is a common complication following orthotopic liver transplantation (OLT) and is associated with increased morbidity and mortality. The aim of the current study was to determine the risk factors for AKI in patients undergoing OLT. A total of 103 patients who received OLT between January 2015 and May 2016 in Tongji Hospital, China, were retrospectively analyzed. Their demographic characteristics and perioperative parameters were collected, and AKI was diagnosed using 2012 Kidney Disease: Improving Global Outcomes (KDIGO) staging criteria. It was found that the incidence of AKI was 40.8% in this cohort and AKI was significantly associated with body mass index, urine volume, operation duration (especially > 480 min), and the postoperative use of vasopressors. It was concluded that relative low urine output, long operation duration, and the postoperative use of vasopressors are risk factors for AKI following OLT.

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原位肝移植后急性肾损伤的危险因素:单中心数据分析。

急性肾损伤(AKI)是原位肝移植(OLT)后常见的并发症，与发病率和死亡率增加有关。本研究的目的是确定接受OLT的患者发生AKI的危险因素。回顾性分析2015年1月至2016年5月在同济医院接受OLT治疗的103例患者。收集他们的人口学特征和围手术期参数，并使用2012肾脏疾病:改善全球预后(KDIGO)分期标准诊断AKI。研究发现，该队列中AKI的发生率为40.8%，AKI与体重指数、尿量、手术时间(尤其是> 480 min)和术后血管加压药物的使用有显著相关性。由此可见，相对低的尿量、较长的手术时间和术后使用血管加压药物是OLT后AKI的危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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