[Chronic ischemia of the brain: state structurally functional properties of erythrocytes ].

Abstract

At patients with a chronic ischemia of a brain against an idiopathic hypertensia of the II stage development intra erythrocyte «an oxidative stress», depression of sorption ability of erythrocytes, change in a membrane of cells of a ratio of fractions of lipids due to decrease of the maintenance of glitserophospholipid and a sphingomyelin, augmentation of a lizophosphatidilkholin, cholesterol is taped. Change of presentability of the membranous proteins responsible for structurization and stabilization of a membrane of erythrocytes, a shaping, flexibility of a membrane and an intracellular metabolism is established. The important role of erythrocytes at a chronic ischemia of a brain based on the concept of their participation in a chain of the adaptive mechanisms supporting a homeostasis is noted.