Restless legs syndrome is contributing to fatigue and low quality of life levels in hemodialysis patients.

Christoforos D Giannaki, Michael Hadjigavriel, Akis Lazarou, Aristos Michael, Loukas Damianou, Efthimios Atmatzidis, Ioannis Stefanidis, Georgios M Hadjigeorgiou, Giorgos K Sakkas, Marios Pantzaris
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引用次数: 21

Abstract

Aim: To examine whether hemodialysis (HD) patients with restless legs syndrome (RLS) are subjects of greater fatigue and impaired quality of life (QoL) compared to HD patients without RLS.

Methods: Eighty five stable HD patients participated in this study. According to their RLS status, the patients were divided into the RLS group (n = 23) and the non-RLS group (n = 62). QoL, fatigue, sleep quality, daily sleepiness and depression symptoms were assessed by using various questionnaires. Finally, biochemical parameters including iron, ferritin, hemoglobin, hematocrit and parathormone were assessed.

Results: The HD patients with RLS scored worse in all the questionnaires used in the study (P < 0.05). The patients with RLS were more likely to receive the HD therapy on the morning shift, whilst 43.5% of the RLS patients reported to experience the RLS symptoms also during HD. The severity of RLS was correlated with fatigue, depression score and sleep quality (P < 0.05).

Conclusion: HD patients with RLS are subject to lower QoL related parameters and greater fatigue compared to HD patients without RLS. RLS should be successfully managed in order to improve the QoL of the sufferers.

不宁腿综合征是导致血液透析患者疲劳和低生活质量水平的原因。
目的:探讨血液透析(HD)伴不宁腿综合征(RLS)患者是否比不伴不宁腿综合征(RLS)的HD患者更容易疲劳和生活质量(QoL)受损。方法:85例稳定期HD患者参与本研究。根据患者的RLS状态将患者分为RLS组(n = 23)和非RLS组(n = 62)。采用各种问卷对患者的生活质量、疲劳程度、睡眠质量、日常嗜睡和抑郁症状进行评估。最后评估生化指标,包括铁、铁蛋白、血红蛋白、红细胞压积和甲状旁激素。结果:HD合并RLS患者在问卷调查中的得分均较差(P < 0.05)。RLS患者更有可能在早班接受HD治疗,而43.5%的RLS患者报告在HD期间也经历了RLS症状。RLS严重程度与疲劳、抑郁评分、睡眠质量相关(P < 0.05)。结论:伴RLS的HD患者与无RLS的HD患者相比,其生活质量相关参数较低,疲劳程度较高。为了提高患者的生活质量,必须对RLS进行有效的控制。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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