Alison L Huckenpahler, Melissa A Wilk, Robert F Cooper, Francie Moehring, Brian A Link, Joseph Carroll, Ross F Collery
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引用次数: 0
Abstract
Fig. 2. Deriving the lateral scale of in vivo OCT images of the fl i1 : eGFP zebrafi sh retina. ( A ) En face image generated by positioning the custom contour within the RNFL. Measurements (in pixels) were taken between multiple blood vessel branch points (white dots). ( B ) Corresponding ex vivo fl uorescent microscopy image of the same retina, with measurements (in μm) taken between the same blood vessel branch points in ( A ). The OCT:microscopy measurements were averaged for each eye and used to determine the size of the OCT scan in μm. A scaling coeffi cient for each scan was calculated as the ratio between the measured size of the OCT scan to the nominal OCT scan size (in this case, 1200 μm). ( C ) The scaling coeffi cient for each scan was plotted against the axial length for that eye and fi t with a linear model. Error bars represent one standard deviation for each eye. doi: https://doi.org/10.1017/S0952523816000092 . Published by Cambridge University Press, 17 October, 2016.
期刊介绍:
Visual Neuroscience is an international journal devoted to the publication of experimental and theoretical research on biological mechanisms of vision. A major goal of publication is to bring together in one journal a broad range of studies that reflect the diversity and originality of all aspects of neuroscience research relating to the visual system. Contributions may address molecular, cellular or systems-level processes in either vertebrate or invertebrate species. The journal publishes work based on a wide range of technical approaches, including molecular genetics, anatomy, physiology, psychophysics and imaging, and utilizing comparative, developmental, theoretical or computational approaches to understand the biology of vision and visuo-motor control. The journal also publishes research seeking to understand disorders of the visual system and strategies for restoring vision. Studies based exclusively on clinical, psychophysiological or behavioral data are welcomed, provided that they address questions concerning neural mechanisms of vision or provide insight into visual dysfunction.