Atopic dermatitis: pathogenesis.

Q1 Medicine

Seminars in cutaneous medicine and surgery Pub Date : 2017-09-01 DOI:10.12788/j.sder.2017.036

Emma Guttman-Yassky, Andrea Waldman, Jusleen Ahluwalia, Peck Y Ong, Lawrence F Eichenfield

引用次数: 57

Abstract

Atopic Dermatitis (AD) is a complex inflammatory cutaneous disorder characterized by immune mediated inflammation and epidermal barrier dysfunction. Arising from a complex interplay between environmental and genetic factors, the definitive etiology of AD is perplexing and controversial. Advances in molecular medicine are radically transforming our understanding of AD pathogenesis. Increasing knowledge on the pathogenesis of AD results in novel therapeutic targets and pathways. This article details the pathogenesis section of the Curriculum United for Better Eczema Care (CUBE-C), facilitating primary care and sub-specialist education on the scientific advances driving recent AD therapeutic innovations.

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特应性皮炎:发病机制。

特应性皮炎(AD)是一种以免疫介导的炎症和表皮屏障功能障碍为特征的复杂炎症性皮肤疾病。由于环境和遗传因素之间复杂的相互作用，阿尔茨海默病的确切病因是令人困惑和有争议的。分子医学的进步从根本上改变了我们对阿尔茨海默病发病机制的认识。对阿尔茨海默病发病机制的不断了解导致了新的治疗靶点和途径。本文详细介绍了改善湿疹护理课程联合(CUBE-C)的发病机制部分，促进了初级保健和亚专科教育的科学进步，推动了最近的AD治疗创新。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Seminars in cutaneous medicine and surgery 医学-皮肤病学

CiteScore

4.90

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Seminars in Cutaneous Medicine and Surgery (SCMS) presents well-rounded and authoritative discussions of important clinical areas, especially those undergoing rapid change in the specialty. Each issue, under the direction of the Editors and Guest Editors selected because of their expertise in the subject area, includes the most current information on the diagnosis and management of specific disorders of the skin, as well as the application of the latest scientific findings to patient care.