Theoretical Models of Vascular Pattern Formation.

Abstract

Pattern formation of vascular structure has been extensively studied in vascular biology. Classically the pattern formation process falls into three categories-vasculogenesis, angiogenesis and remodeling. Mathematical modeling study of these phenomena has been done byrelatively independent of experimental works by applied mathematicians, and not well understood by experimental biologists. In this review I provide intuitive explanations of proposed theoretical models and recent advance in modelling study of vascular development.