One case with dexmedetomidine-induced stuporous state in epileptic patient undergoing abdominal surgery.

American journal of neurodegenerative disease Pub Date : 2017-07-25 eCollection Date: 2017-01-01
Dong-Ji Han, Zhi-Gang He, Zhi-Qiang Zhou, Li Feng, Cheng Liu, Yan Xiang, Hong-Bing Xiang
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Abstract

A 56-year-old epileptic patient underwent right hemicolectomy and cholecystectomy surgery under general endotracheal anesthesia. Anesthesia was maintained with sevoflurane, and sufentanil, rocuronium, and dexmedetomidine infusions. After the operation and confirmation of neuromuscular recovery, the patient woke from anesthesia within 15 min and successfully extubated. After the vital signs of patient were stable, the patient was transported to post anesthesia care unit (PACU). 6 h after the surgery, he fell into a stuporous state for lasting 14 h and EEG showed no epileptiform discharges. Stupor did re-occur in 2 days after operation. 36 hours after operation, all signs of the stuporous state resolved spontaneously. Apparent dexmedetomidine-induced stuporous state has not been reported in the human literature.

Abstract Image

Abstract Image

右美托咪定致癫痫腹部手术患者昏迷1例。
56岁癫痫患者在气管全麻下行右半结肠及胆囊切除术。七氟醚、舒芬太尼、罗库溴铵和右美托咪定输注维持麻醉。手术确认神经肌肉恢复后,患者在15分钟内从麻醉中醒来,成功拔管。生命体征稳定后,将患者送往麻醉后护理病房(PACU)。术后6 h进入昏迷状态,持续14 h,脑电图未见癫痫样放电。术后2天再次出现昏迷。术后36小时,昏迷状态的所有症状自行消失。明显的右美托咪定诱导的昏迷状态尚未在人类文献中报道。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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