CART Peptide Regulates Psychostimulant-Induced Activity and Exhibits a Rate Dependency.

Abstract

Since the identification of CART peptides in the 1990s [1], evidence has been steadily accumulating that they are involved in a great variety of physiologic processes. These include feeding and body weight, depression and anxiety, stress, hormonal control, psychostimulant (PS) action [2, 3, 4, 5, 6, 7, 8], and others. With regard to PS action, CART peptides appear to regulate the action of cocaine, amphetamine, and dopamine.