Reformulation of Traditional Chamomile Oil: Quality Controls and Fingerprint Presentation Based on Cluster Analysis of Attenuated Total Reflectance-Infrared Spectral Data.

Arman Zargaran, Amirhossein Sakhteman, Pouya Faridi, Saeid Daneshamouz, Amin Reza Akbarizadeh, Afshin Borhani-Haghighi, Abdolali Mohagheghzadeh
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引用次数: 7

Abstract

Herbal oils have been widely used in Iran as medicinal compounds dating back to thousands of years in Iran. Chamomile oil is widely used as an example of traditional oil. We remade chamomile oils and tried to modify it with current knowledge and facilities. Six types of oil (traditional and modified) were prepared. Microbial limit tests and physicochemical tests were performed on them. Also, principal component analysis, hierarchical cluster analysis, and partial least squares discriminant analysis were done on the spectral data of attenuated total reflectance-infrared in order to obtain insight based on classification pattern of the samples. The results show that we can use modified versions of the chamomile oils (modified Clevenger-type apparatus method and microwave method) with the same content of traditional ones and with less microbial contaminations and better physicochemical properties.

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传统洋甘菊油的改良配方:基于衰减全反射-红外光谱数据聚类分析的质量控制与指纹表征。
草药油在伊朗被广泛用作药用化合物,可以追溯到几千年前的伊朗。洋甘菊油作为一种传统油被广泛使用。我们重新制作了洋甘菊油,并尝试用现有的知识和设备对其进行修改。制备了六种油(传统油和改性油)。对其进行微生物限度试验和理化试验。并对衰减全反射-红外光谱数据进行主成分分析、层次聚类分析和偏最小二乘判别分析,以获得基于样本分类模式的洞察。结果表明,采用改良版的洋甘菊油(改良clevenger型装置法和微波法)可以在与传统方法含量相同的条件下,减少微生物污染,提高理化性能。
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审稿时长
15 weeks
期刊介绍: The Journal of Evidence-Based Integrative Medicine ((JEBIM)), published previously as the Journal of Evidence-Based Complementary and Alternative Medicine (JEBCAM) and also as Complementary Health Practice Review (CHPR). The Journal of Evidence-Based Integrative Medicine (JEBIM) is an interdisciplinary, peer-reviewed, open access, biomedical journal whose aim is to create a global platform for hypothesis-driven and evidence-based research in all fields of integrative medicine. The journal’s objective is to publish papers which impart scientific validity to Integrative Medicine methods that are indispensable and inevitable in today’s world. All papers will be peer reviewed by experts in their respective fields, and papers will be accepted based on their scientific merit. It is the goal of the Journal to help remove the “myth” and provide scientific rationale for the various methodologies and theories of Integrative Medicine. All submissions will be reviewed based on their scientific merit and only papers with sound study design, valid statistical analyses and logical conclusions will be accepted. Topics include, but are not limited to: Traditional Eastern and Western medicine Nutrition therapy and supplementation Massage Therapy Non-traditional treatments Preventative medicine Integrative health and medicine Mindfulness Yoga.
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