{"title":"Estimation of Platelet Counts and Other Hematological Parameters in Pseudothrombocytopenia Using Alternative Anticoagulant: Magnesium Sulfate.","authors":"Chidambharam Choccalingam, Rajesh Kanna Nandagopal Radha, Nadella Snigdha","doi":"10.1177/1179545X17705380","DOIUrl":null,"url":null,"abstract":"<p><p>The platelet count, mean platelet volume, and other hematological parameters were compared in blood samples anticoagulated with MgSO<sub>4</sub> and EDTA. A total of 15 samples were taken, and the platelet counts were observed to be significantly high in MgSO<sub>4</sub>-anticoagulated blood samples ranging from 53 × 10<sup>3</sup> to 499 × 10<sup>3</sup>/μL, whereas in EDTA-anticoagulated blood samples, the counts ranged from 10 × 10<sup>3</sup> to 353 × 10<sup>3</sup>/μL. This increased platelet count was also statistically significant with the <i>P</i> value being .005. The morphology of red blood cells and white blood cells in Leishman-stained smears from MgSO<sub>4</sub>-anticoagulated blood was below average. In conclusion, MgSO<sub>4</sub> can be used as an alternative anticoagulant only to estimate the platelet counts in EDTA-induced pseudothrombocytopenia.</p>","PeriodicalId":43083,"journal":{"name":"Clinical Medicine Insights-Blood Disorders","volume":null,"pages":null},"PeriodicalIF":3.0000,"publicationDate":"2017-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/1179545X17705380","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Medicine Insights-Blood Disorders","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/1179545X17705380","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 5
Abstract
The platelet count, mean platelet volume, and other hematological parameters were compared in blood samples anticoagulated with MgSO4 and EDTA. A total of 15 samples were taken, and the platelet counts were observed to be significantly high in MgSO4-anticoagulated blood samples ranging from 53 × 103 to 499 × 103/μL, whereas in EDTA-anticoagulated blood samples, the counts ranged from 10 × 103 to 353 × 103/μL. This increased platelet count was also statistically significant with the P value being .005. The morphology of red blood cells and white blood cells in Leishman-stained smears from MgSO4-anticoagulated blood was below average. In conclusion, MgSO4 can be used as an alternative anticoagulant only to estimate the platelet counts in EDTA-induced pseudothrombocytopenia.
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