Pancreas Transplant at the University of Maryland.

Clinical transplants Pub Date : 2015-01-01
Soo Y Yi, Katie Shaw, Nadiesda Costa, David B Leeser
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Abstract

The characteristic of our diabetic population has been ever changing. No longer are our Type 1 diabetics young and thin; they too suffer from the obesity epidemic and now present later with the complications of diabetes (renal dysfunction, hypoglycemic unawareness, vision loss, neuropathy, etc.). Even with all of our medical and technological advances to combat diabetes, there are many who are not very well controlled. We evaluated the pancreas transplant recipients in the last three years at the University of Maryland to study the outcomes of these older and higher body mass index (BMI) recipients, as well as the impact of using older and higher BMI donors. We saw no difference in the survival of the patient or the allograft of recipients who were older or had higher BMIs. We also saw no difference in morbidity for these patients. There also was no difference when using older or higher BMI donor organs, longer cold ischemic times, different types of donors (donation after cardiac death versus brain dead donors), or different types of organs (simultaneous pancreas kidney, pancreas transplant alone, or pancreas after kidney). In reviewing our waitlist, our patients range widely in age and BMI. As long as they are fit for surgery, we will continue to transplant our ever growing population of older and obese diabetics without any more adverse outcomes than occur in our normal weight and younger patients.

在马里兰大学进行胰腺移植。
我国糖尿病人群的特点是不断变化的。我们的1型糖尿病患者不再年轻和苗条;他们也患有肥胖症,后来又出现了糖尿病的并发症(肾功能障碍、低血糖无意识、视力丧失、神经病变等)。即使我们在对抗糖尿病方面取得了所有的医学和技术进步,仍有许多人没有得到很好的控制。我们对马里兰大学过去三年的胰腺移植受者进行了评估,以研究这些年龄较大和身体质量指数(BMI)较高的受者的结果,以及使用年龄较大和身体质量指数较高的供者的影响。我们没有看到年龄较大或bmi较高的患者或同种异体移植的存活率有什么不同。我们也发现这些病人的发病率没有差别。当使用年龄较大或BMI较高的供体器官、较长的冷缺血时间、不同类型的供体(心脏死亡后捐赠与脑死亡后捐赠)或不同类型的器官(同时胰肾移植、单独胰肾移植或胰肾后移植)时,也没有差异。在回顾我们的等待名单时,我们的病人在年龄和体重指数上差别很大。只要他们适合手术,我们将继续移植我们不断增长的老年和肥胖糖尿病患者,而不会出现比正常体重和年轻患者更多的不良后果。
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