{"title":"In Vitro Antimicrobial Activity of Thymus vulgaris Essential Oil Against Major Oral Pathogens.","authors":"Mohammadmehdi Fani, Jamshid Kohanteb","doi":"10.1177/2156587217700772","DOIUrl":null,"url":null,"abstract":"<p><p>The objective of present investigation was to determine antimicrobial activity of Thymus vulgaris oil on some oral pathogens. Thymus vulgaris oil was prepared by hydrodistillation and tested against 30 clinical isolates of each of Streptococcus pyogenes, Streptococcus mutans, Candida albicans, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans, prepared from related oral infections using agar disk diffusion and broth microdilution methods. Thymus vulgaris oil at concentrations of 16 to 256 μg/mL exhibited strong inhibitory activity on all clinical isolates producing inhibition zones of 7.5 to 42 mm as measured by agar disk diffusion method. Streptococcus pyogenes and Streptococcus mutans were the most sensitive isolates with minimum inhibitory concentrations of 1.9 and 3.6 μg/mL, respectively. The minimum inhibitory concentration values for C albicans, A actinomycetemcomitans, and P gingivalis were 16.3, 32, and 32 μg/mL, respectively.</p>","PeriodicalId":15804,"journal":{"name":"Journal of Evidence-Based Complementary & Alternative Medicine","volume":"22 4","pages":"660-666"},"PeriodicalIF":0.0000,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1177/2156587217700772","citationCount":"63","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Evidence-Based Complementary & Alternative Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/2156587217700772","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2017/4/11 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 63
Abstract
The objective of present investigation was to determine antimicrobial activity of Thymus vulgaris oil on some oral pathogens. Thymus vulgaris oil was prepared by hydrodistillation and tested against 30 clinical isolates of each of Streptococcus pyogenes, Streptococcus mutans, Candida albicans, Porphyromonas gingivalis, and Aggregatibacter actinomycetemcomitans, prepared from related oral infections using agar disk diffusion and broth microdilution methods. Thymus vulgaris oil at concentrations of 16 to 256 μg/mL exhibited strong inhibitory activity on all clinical isolates producing inhibition zones of 7.5 to 42 mm as measured by agar disk diffusion method. Streptococcus pyogenes and Streptococcus mutans were the most sensitive isolates with minimum inhibitory concentrations of 1.9 and 3.6 μg/mL, respectively. The minimum inhibitory concentration values for C albicans, A actinomycetemcomitans, and P gingivalis were 16.3, 32, and 32 μg/mL, respectively.
期刊介绍：
The Journal of Evidence-Based Integrative Medicine ((JEBIM)), published previously as the Journal of Evidence-Based Complementary and Alternative Medicine (JEBCAM) and also as Complementary Health Practice Review (CHPR). The Journal of Evidence-Based Integrative Medicine (JEBIM) is an interdisciplinary, peer-reviewed, open access, biomedical journal whose aim is to create a global platform for hypothesis-driven and evidence-based research in all fields of integrative medicine. The journal’s objective is to publish papers which impart scientific validity to Integrative Medicine methods that are indispensable and inevitable in today’s world. All papers will be peer reviewed by experts in their respective fields, and papers will be accepted based on their scientific merit. It is the goal of the Journal to help remove the “myth” and provide scientific rationale for the various methodologies and theories of Integrative Medicine. All submissions will be reviewed based on their scientific merit and only papers with sound study design, valid statistical analyses and logical conclusions will be accepted. Topics include, but are not limited to: Traditional Eastern and Western medicine Nutrition therapy and supplementation Massage Therapy Non-traditional treatments Preventative medicine Integrative health and medicine Mindfulness Yoga.
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