A 15-year epileptogenic period after perinatal brain injury.

Q2 Medicine
F Pisani, E Pavlidis, C Facini, C La Morgia, C Fusco, G Cantalupo
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引用次数: 7

Abstract

Seizures are a frequent acute neurological event in the neonatal period. Up to 12 to 18% of all seizures in newborns are due to perinatal stroke and up to 39% of affected children can then develop epilepsy in childhood. We report the case of a young patient who presented stroke-related seizures in the neonatal period and then developed focal symptomatic epilepsy at 15 years of age, and in whom the epileptic focus was found to co-localize with the site of his ischemic brain lesion. Such a prolonged silent period before onset of remote symptomatic epilepsy has not previously been reported. This case suggests that newborns with seizures due to a neonatal stroke are at higher risk of epilepsy and that the epileptogenic process in these subjects can last longer than a decade.

Abstract Image

Abstract Image

围产期脑损伤后15年的癫痫发病期。
癫痫发作是新生儿期常见的急性神经系统事件。在所有新生儿癫痫发作中,多达12%至18%是由于围产期中风造成的,多达39%的受影响儿童可在儿童期发展为癫痫。我们报告一例年轻患者,他在新生儿时期出现卒中相关癫痫发作,然后在15岁时发展为局灶性症状性癫痫,在他的癫痫灶被发现与他的缺血性脑损伤部位共定位。远端症状性癫痫发作前如此长时间的沉默期以前未见报道。本病例提示,新生儿中风后癫痫发作的新生儿癫痫风险较高,这些患者的癫痫发病过程可持续10年以上。
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来源期刊
Functional neurology
Functional neurology 医学-神经科学
CiteScore
3.90
自引率
0.00%
发文量
0
审稿时长
>12 weeks
期刊介绍: Information not localized
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