A Case Report of Syndrome of Inappropriate Antidiuretic Hormone Induced by Pregabalin.

Q3 Medicine
Electrolyte and Blood Pressure Pub Date : 2016-12-01 Epub Date: 2016-12-31 DOI:10.5049/EBP.2016.14.2.31
Youn Joo Jung, Dong-Young Lee, Hae Won Kim, Hyun Sun Park, Beom Kim
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引用次数: 7

Abstract

The syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common cause of euvolemic hyponatremia, and many medications have been associated with SIADH. Pregabalin is a drug used for the treatment of neuropathic pain, though common adverse effects include central nervous system disturbance, peripheral edema, and weight gain. However, hyponatremia caused by pregabalin has been rarely reported. Here we report a patient with pregabalin-induced hyponatremia who met the criteria for SIADH; after discontinuation of the drug, his condition rapidly improved. This case can help clinicians diagnose and treat new-onset hyponatremia in patients who recently initiated pregabalin therapy.

Abstract Image

Abstract Image

普瑞巴林致抗利尿激素不适宜综合征1例报告。
抗利尿激素分泌不当综合征(SIADH)是低血容量性低钠血症的最常见原因,许多药物与SIADH有关。普瑞巴林是一种用于治疗神经性疼痛的药物,但常见的副作用包括中枢神经系统紊乱、外周水肿和体重增加。然而普瑞巴林引起的低钠血症鲜有报道。在这里,我们报告了一位普瑞巴林诱导的低钠血症患者,他符合SIADH的标准;停药后,他的病情迅速好转。本病例可以帮助临床医生诊断和治疗新近开始普瑞巴林治疗的新发低钠血症患者。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Electrolyte and Blood Pressure
Electrolyte and Blood Pressure Medicine-Internal Medicine
CiteScore
2.10
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0.00%
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