Prevalence of Major Cardiovascular Risk Factors and Coronary Heart Disease in a Sample of Greek Adults: The Saronikos Study.

The Open Cardiovascular Medicine Journal Pub Date : 2016-05-24 eCollection Date: 2016-01-01 DOI:10.2174/1874192401610010069
Aristofanis Gikas, Vaia Lambadiari, Alexios Sotiropoulos, Demosthenes Panagiotakos, Stavros Pappas
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引用次数: 22

Abstract

Background: Comprehensive data regarding prevalence of coronary heart disease (CHD) and associated factors in different geographical regions are very important to our understanding of global distribution and evolution of CHD. The aim of this study was to assess the current prevalence of self-reported risk factors and CHD in Greek adult population.

Methods: A community-based cross-sectional study was conducted in May 2014, during an election day, among residents of Saronikos municipality (Attica region). Data were collected from face-to-face interviews. The study sample included 2636 subjects (men, 49.5%; mean age, 50.5; range 20-95 years), with similar age and sex distribution to the target population.

Results: The age-standardized prevalence rates of five major risk factors were as follows: type 2 diabetes 11.1%, hypercholesterolemia (cholesterol>240 mg/dl or using cholesterol-lowering medication) 23.8%, hypertension 27.2%, current smoking 38.9% and physical inactivity 43%. Of the participants, only 21% were free of any of these factors. Clustering of two to five risk factors was more frequent among persons aged 50 years and older as compared with younger ones (60% vs 27%, P=0.000). The age-adjusted prevalence of CHD was 6.3% (in men, 8.9%; in women, 3.8%) and that of myocardial infarction was 3.6% (in men, 5.2%; in women, 2.1%). According to multivariate analysis age, gender, education level, obesity, diabetes, hypercholesterolemia, hypertension and ever smoking were strongly associated with CHD.

Conclusion: Classic risk factors are highly prevalent and frequently clustered, especially in adults aged 50 years and older. These findings raise concerns about future trends of already increased rates of CHD. Multifactorial and integrated population-based interventions need to be applied to reduce the burden of cardiovascular conditions.

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主要心血管危险因素和冠心病在希腊成年人样本中的流行:Saronikos研究
背景:不同地理区域冠心病患病率及相关因素的综合数据对我们了解冠心病的全球分布和演变非常重要。本研究的目的是评估目前希腊成年人自我报告的危险因素和冠心病的流行程度。方法:2014年5月选举日期间,在萨罗尼科斯市(阿提卡地区)的居民中进行了一项基于社区的横断面研究。数据收集自面对面访谈。研究样本包括2636名受试者(男性49.5%;平均年龄50.5岁;年龄介乎20至95岁),年龄及性别分布与目标人群相近。结果:5个主要危险因素的年龄标准化患病率分别为:2型糖尿病11.1%、高胆固醇血症(胆固醇>240 mg/dl或使用降胆固醇药物)23.8%、高血压27.2%、吸烟38.9%、缺乏运动43%。在参与者中,只有21%的人没有这些因素。与年轻人相比,50岁及以上人群中两到五个危险因素的聚类更常见(60%比27%,P=0.000)。经年龄调整的冠心病患病率为6.3%(男性为8.9%;女性为3.8%),心肌梗死的发生率为3.6%(男性为5.2%;女性为2.1%)。多因素分析显示,年龄、性别、文化程度、肥胖、糖尿病、高胆固醇血症、高血压、是否吸烟与冠心病密切相关。结论:典型危险因素在50岁及以上人群中发病率高,聚集性强。这些发现引起了人们对已经增加的冠心病发病率的未来趋势的关注。需要采用多因素和基于人群的综合干预措施来减轻心血管疾病的负担。
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