Validating a measure of myalgic encephalomyelitis/chronic fatigue syndrome symptomatology.

IF 2.2 Q3 MEDICINE, RESEARCH & EXPERIMENTAL

Fatigue-Biomedicine Health and Behavior Pub Date : 2014-01-01 Epub Date: 2014-07-23 DOI:10.1080/21641846.2014.928014

Abigail A Brown, Leonard A Jason

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引用次数: 68

Abstract

Objectives: The present study sought to validate a comprehensive self-report measure of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) symptomatology to aid in clinical and research assessment.

Method: Exploratory factor analysis (EFA) was used to establish the underlying factor structure of the DePaul Symptom Questionnaire (DSQ) (Jason, Evans, et al., 2010) using a well-characterized sample of individuals (92.6% met the Fukuda et al. criteria (1994) and/or the Clinical Canadian Criteria (Carruthers et al., 2003)), and this structure was then tested on a less stringently recruited sample of individuals utilizing a confirmatory factor analysis (CFA). Convergent and discriminant validity of the DSQ were also examined utilizing alternative measures of symptomatology and functioning.

Results: A 3-factor solution was found using EFA (Neuroendocrine, Autonomic & Immune Dysfunction; Neurological/Cognitive Dysfunction; Post-Exertional Malaise) and the fit of this factor structure was adequate for the second sample.

Discussion: The DSQ is a valid measure of ME/CFS symptomatology. The emergent factors were consistent with previous literature on symptom clusters, and convergent and discriminant validity were established.

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验证肌痛性脑脊髓炎/慢性疲劳综合征症状的测量方法。

目的:本研究旨在验证肌痛性脑脊髓炎/慢性疲劳综合征(ME/CFS)症状学的综合自我报告测量，以帮助临床和研究评估。方法:探索性因素分析(EFA)用于建立DePaul症状问卷(DSQ)的潜在因素结构(Jason, Evans, et al.， 2010)，使用特征明确的个体样本(92.6%符合Fukuda等人的标准(1994)和/或加拿大临床标准(Carruthers等人，2003))，然后使用验证性因素分析(CFA)在招募不那么严格的个体样本上测试该结构。我们还利用症状学和功能的替代测量来检验DSQ的收敛效度和判别效度。结果:采用EFA(神经内分泌、自主神经和免疫功能障碍;神经系统/认知功能障碍;运动后不适)，该因素结构的拟合对第二个样本来说是足够的。讨论:DSQ是ME/CFS症状的有效测量方法。出现因素与文献对症状聚类的研究结果一致，并建立了收敛效度和判别效度。

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来源期刊

Fatigue-Biomedicine Health and Behavior MEDICINE, RESEARCH & EXPERIMENTAL-

CiteScore

5.20

自引率

7.10%

发文量

期刊介绍： Fatigue: Biomedicine, Health and Behavior is an international, interdisciplinary journal that addresses the symptom of fatigue in medical illnesses, behavioral disorders, and specific environmental conditions. These broadly conceived domains, all housed in one journal, are intended to advance research on causation, pathophysiology, assessment, and treatment. The list of topics covered in Fatigue will include fatigue in diseases including cancer, autoimmune diseases, multiple sclerosis, pain conditions, mood disorders, and circulatory diseases. The journal will also publish papers on chronic fatigue syndrome, fibromyalgia and related illnesses. In addition, submissions on specific issues involving fatigue in sleep, aging, exercise and sport, and occupations are welcomed. More generally, the journal will publish on the biology, physiology and psychosocial aspects of fatigue. The Editor also welcomes new topics such as clinical fatigue education in medical schools and public health policy with respect to fatigue.