Actinic Keratosis Pathogenesis Update and New Patents.

IF 4.2 Q3 Pharmacology, Toxicology and Pharmaceutics
Carmen Cantisani, Giovanni Paolino, Marcello Melis, Valentina Faina, Federico Romaniello, Dario Didona, Michele Cardone, Stefano Calvieri
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引用次数: 11

Abstract

Background: Actinic keratosis is a common premalignant skin lesion. Because of its increasing incidence, several efforts have been made to earlier detectection and to improve knowledge on photocarcinogenic pathways of keratinocytes. As a consequence, recently new discoveries have been done in this field.

Objective: Starting from our previous review on actinic keratosis, we reviewed the literature focusing on pathogenesis and new patents in order to highlight the most recent progresses in diagnosis and therapeutic approach.

Conclusion: Although several efforts have been done in the field of photodamaged skin, new upgrades in diagnosis and therapy are needed to detect superficial actinic keratosis earlier, to improve the disease free survival of patient and to better treat the field cancerization.

光化性角化病发病机制最新进展及新专利。
背景:光化性角化病是一种常见的恶性皮肤病变。由于其发病率越来越高,人们已经做出了一些努力来早期发现并提高对角化细胞光致癌途径的认识。因此,最近在这个领域有了新的发现。目的:在回顾光化性角化病相关文献的基础上,回顾光化性角化病的发病机制和新专利,总结其诊断和治疗方法的最新进展。结论:虽然在光损伤皮肤领域已经做了一些努力,但为了早期发现浅浅光化性角化病,提高患者的无病生存期,更好地治疗野区癌变,还需要在诊断和治疗方面有新的提升。
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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
0
期刊介绍: Recent Patents on Inflammation & Allergy Drug Discovery publishes review articles by experts on recent patents in the field of inflammation and allergy drug discovery e.g. on novel bioactive compounds, analogs and targets. A selection of important and recent patents in the field is also included in the journal. The journal is essential reading for all researchers involved in inflammation and allergy drug design and discovery.
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