The biological challenge of myalgic encephalomyelitis/chronic fatigue syndrome: a solvable problem.

IF 2.2 Q3 MEDICINE, RESEARCH & EXPERIMENTAL
Jonathan C W Edwards, Simon McGrath, Adrian Baldwin, Mark Livingstone, Andrew Kewley
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引用次数: 13

Abstract

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is comparable to multiple sclerosis, diabetes or rheumatoid arthritis in prevalence (∼0.2% to 1%), long-term disability, and quality of life,[1–5] yet the scale of biomedical research and funding has been pitifully limited, as the recent National Institutes of Health (NIH) and Institute of Medicine reports highlight.[6,7] Recently in the USA, NIH Director Francis Collins has stated that the NIH will be ramping up its efforts and levels of funding for ME/CFS,[8] which we hope will greatly increase the interest in, and resources for researching this illness. Despite scant funding to date, researchers in the field have generated promising leads that throw light on this previously baffling illness. We suggest the key elements of a concerted research programme and call on the wider biomedical research community to actively target this condition.
肌痛性脑脊髓炎/慢性疲劳综合征的生物学挑战:一个可解决的问题。
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来源期刊
Fatigue-Biomedicine Health and Behavior
Fatigue-Biomedicine Health and Behavior MEDICINE, RESEARCH & EXPERIMENTAL-
CiteScore
5.20
自引率
7.10%
发文量
16
期刊介绍: Fatigue: Biomedicine, Health and Behavior is an international, interdisciplinary journal that addresses the symptom of fatigue in medical illnesses, behavioral disorders, and specific environmental conditions. These broadly conceived domains, all housed in one journal, are intended to advance research on causation, pathophysiology, assessment, and treatment. The list of topics covered in Fatigue will include fatigue in diseases including cancer, autoimmune diseases, multiple sclerosis, pain conditions, mood disorders, and circulatory diseases. The journal will also publish papers on chronic fatigue syndrome, fibromyalgia and related illnesses. In addition, submissions on specific issues involving fatigue in sleep, aging, exercise and sport, and occupations are welcomed. More generally, the journal will publish on the biology, physiology and psychosocial aspects of fatigue. The Editor also welcomes new topics such as clinical fatigue education in medical schools and public health policy with respect to fatigue.
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