Low-Dose PET/CT and Full-Dose Contrast-Enhanced CT at the Initial Staging of Localized Diffuse Large B-Cell Lymphomas.

IF 3 Q2 Medicine
Clinical Medicine Insights-Blood Disorders Pub Date : 2016-08-17 eCollection Date: 2016-01-01 DOI:10.4137/CMBD.S38468
Aida Sabaté-Llobera, Montserrat Cortés-Romera, Santiago Mercadal, Javier Hernández-Gañán, Helena Pomares, Eva González-Barca, Cristina Gámez-Cenzano
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引用次数: 7

Abstract

Computed tomography (CT) has been used as the reference imaging technique for the initial staging of diffuse large B-cell lymphoma until recent days, when the introduction of positron emission tomography (PET)/CT imaging as a hybrid technique has become of routine use. However, the performance of both examinations is still common. The aim of this work was to compare the findings between low-dose 2-deoxy-2-((18)F)fluoro-d-glucose ((18)F-FDG) PET/CT and full-dose contrast-enhanced CT (ceCT) in 28 patients with localized diffuse large B-cell lymphoma according to PET/CT findings, in order to avoid the performance of ceCT. For each technique, a comparison in the number of nodal and extranodal involved regions was performed. PET/CT showed more lesions than ceCT in both nodal (41 vs. 36) and extranodal localizations (16 vs. 15). Disease staging according to both techniques was concordant in 22 patients (79%) and discordant in 6 patients (21%), changing treatment management in 3 patients (11%). PET/CT determined a better staging and therapeutic approach, making the performance of an additional ceCT unnecessary.

Abstract Image

局部弥漫性大b细胞淋巴瘤初始分期的低剂量PET/CT和全剂量增强CT。
计算机断层扫描(CT)一直被用作弥漫性大b细胞淋巴瘤初始分期的参考成像技术,直到最近,正电子发射断层扫描(PET)/CT成像作为一种混合技术的引入已成为常规使用。然而,这两种考试的表现仍然很普遍。本研究的目的是比较低剂量2-脱氧-2-(18)F)氟-d-葡萄糖(18)F- fdg) PET/CT与全剂量对比增强CT (ceCT)在28例局部弥漫性大b细胞淋巴瘤患者中的表现,以避免ceCT的表现。对于每种技术,在淋巴结和结外受累区域的数量进行比较。PET/CT在淋巴结(41比36)和结外定位(16比15)中显示的病变都比ceCT多。根据两种技术进行的疾病分期22例(79%)一致,6例(21%)不一致,3例(11%)改变了治疗方法。PET/CT确定了更好的分期和治疗方法,使额外的ceCT的性能变得不必要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.70
自引率
0.00%
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审稿时长
8 weeks
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