[USE OF QuantiFERON-TB Gold in Tube AND T-SPOT.TB FOR DIAGNOSING PATIENTS WITH SUSPECTED PULMONARY TUBERCULOSIS].

Kekkaku : [Tuberculosis] Pub Date : 2016-04-01

Niro Okimoto, Takeyuki Kurihara, Naoyuki Miyashita

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Abstract

Objective: We analyzed the use of QFT-TB Gold in Tube and T-SPOT.TB in diagnosing patients with suspected pulmonary tuberculosis.

Subjects and methods: We evaluated 122 patients with suspected pulmonary tuberculosis (where chest X-ray showed consolidation or. tumor shadow in predilection sites of pulmonary tuberculosis and through contact investigation). QFT-TB Gold and T-SPOT.TB were performed for all the patients. The positive response rate and history of pulmonary tuberculosis in patients who showed positive results for the tests were evaluated.

Results: Ninteen patients showed positive results for QFT-TB Gold, and 9, for T-SPOT.TB. Four patients showed positive results for QFT-TB Gold, and 3, for T-SPOT.TB in 4 patients with active tuberculosis. The patients without active tuberculosis whose IGRAs were positive (old pulmonary tuberculosis, Mycobacterium avium cmplex, pneumonia, lung cancer, pulmonary sequestration, bronchiectasis) had a past history of pulmonary tuberculosis.

Conclusion: The positive result rate of QFT?-TB Gold was higher than that of T-SPOT.TB in the subjects with suspected pulmonary tuberculosis. We think that QFT-TB Gold reflected the past history of pulmonary tuberculosis.

本刊更多论文

定量铁- tb金在试管和t点中的应用。结核病用于诊断疑似肺结核患者]。

目的:分析QFT-TB金在试管和T-SPOT中的应用。结核在诊断疑似肺结核患者中的作用。研究对象和方法:我们评估了122例疑似肺结核患者(胸部x线片显示实变或结核)。肺结核易发部位的肿瘤影(通过接触者调查)。QFT-TB Gold和T-SPOT。所有患者均行TB检查。对检测结果呈阳性的患者的阳性反应率和肺结核病史进行了评估。结果:9例患者QFT-TB Gold阳性，9例患者T-SPOT.TB阳性。4例患者QFT-TB Gold阳性，3例T-SPOT阳性。4例活动性结核病患者。IGRAs阳性的非活动性肺结核患者(老年性肺结核、鸟分枝杆菌复合体、肺炎、肺癌、肺隔离、支气管扩张)既往有肺结核病史。结论:QFT的阳性检出率?-TB Gold高于T-SPOT。肺结核疑似病例。我们认为QFT-TB Gold反映了肺结核的既往病史。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Kekkaku : [Tuberculosis]

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