Invasive pneumococcal disease in Australia, 2011 and 2012.

IF 1.6 Q4 INFECTIOUS DISEASES
Communicable Diseases Intelligence Pub Date : 2016-06-30
Cindy Toms, Rachel de Kluyver
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Abstract

In Australia, there were 1,883 cases (8.3 per 100,000 population) of invasive pneumococcal disease (IPD) notified to the National Notifiable Diseases Surveillance System (NNDSS) in 2011 and 1,823 cases (8.0 per 100,000) in 2012. The overall rate of IPD in Indigenous Australians was 9 times the rate of IPD in non-Indigenous Australians in 2011 and 7 times in 2012. Following the July 2011 introduction of the 13-valent pneumococcal conjugate vaccine (13vPCV) to the National Immunisation Program, rates of IPD in children aged less than 5 years decreased from 19.5 per 100,000 in 2011 to 12.6 per 100,000 in 2012. In Indigenous adults aged 50 years or over the rates of IPD caused by serotypes included in the 23-valent pneumococcal polysaccharide vaccine (23vPPV) continued to increase in both 2011 (47.2 per 100,000) and 2012 (51.2 per 100,000). The rates of IPD in non-Indigenous adults aged 65 years or over caused by serotypes included in the 23vPPV also increased in 2011 (10.1 per 100,000) and 2012 (11.2 per 100,000). There were 134 deaths attributable to IPD in 2011 and 126 in 2012, although it should be noted that deaths may be under-reported. The number of invasive pneumococcal isolates with reduced penicillin susceptibility remained low and reduced susceptibility to ceftriaxone/cefotaxime continued to be rare.

2011年和2012年澳大利亚侵袭性肺炎球菌病
在澳大利亚,2011年向国家法定疾病监测系统(NNDSS)报告了1883例(每10万人8.3例)侵袭性肺炎球菌病(IPD), 2012年报告了1823例(每10万人8.0例)。2011年,澳大利亚土著居民患IPD的总体比率是非土著澳大利亚人患IPD的9倍,2012年为7倍。在2011年7月将13价肺炎球菌结合疫苗(13vPCV)引入国家免疫规划之后,5岁以下儿童的IPD发病率从2011年的19.5 / 10万下降到2012年的12.6 / 10万。在50岁或以上的土著成年人中,由23价肺炎球菌多糖疫苗(23vPPV)所含血清型引起的IPD发生率在2011年(每10万人47.2例)和2012年(每10万人51.2例)继续增加。2011年(每10万人10.1例)和2012年(每10万人11.2例),由23vPPV中包含的血清型引起的65岁或以上非土著成年人IPD发生率也有所增加。2011年有134人死于IPD, 2012年有126人死于IPD,但应当指出,死亡人数可能少报。青霉素敏感性降低的侵袭性肺炎球菌分离株数量仍然很低,对头孢曲松/头孢噻肟敏感性降低的病例仍然很少见。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Communicable Diseases Intelligence
Communicable Diseases Intelligence INFECTIOUS DISEASES-
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