Spinal Burkitt's Lymphoma Mimicking Dumbbell Shape Neurogenic Tumor: A Case Report and Review of the Literature.

Korean Journal of Spine Pub Date : 2015-09-01 Epub Date: 2015-09-30 DOI:10.14245/kjs.2015.12.3.221
You-Sub Kim, Jung-Kil Lee, Ki-Young Choi, Jae-Won Jang
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引用次数: 7

Abstract

Non-Hodgkin's lymphoma (NHL), a disease which may involve the spine, is frequently associated with advanced disease. Radiculopathy caused by spinal root compression as the initial presentation in patients with NHL is very rare and thought to occur in less than 5% of cases. A 69-year-old woman complained of a history of low back pain with right sciatica for 1 month prior to admission. Computed tomography and magnetic resonance imaging of the lumbar spine showed a dumbbell-shape epidural mass lesion extending from L2 to L3, which was suggestive of a neurogenic tumor. After paraspinal approach and L2 lower half partial hemilaminectomy, total excision of the tumor was achieved, followed by rapid improvement of back pain and radiating pain. The lesion was confirmed to be Burkitt's lymphoma by histopathological examination. We then checked whole-body PET-CT, which showed multifocal malignant lesions in the intestine, liver, bone and left supraclavicular lymph node. Although a rare situation, Burkitt's lymphoma should be considered in the differential diagnosis for patients presenting with back and lumbar radicular pain without a prior history of malignancy. Burkitt's lymphoma could be the cause of dumbbell-shape spinal tumor.

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脊柱Burkitt淋巴瘤模拟哑铃状神经源性肿瘤:1例报告及文献复习。
非霍奇金淋巴瘤(NHL),一种可能累及脊柱的疾病,通常与晚期疾病相关。以脊髓根受压引起的神经根病作为NHL患者的初始表现是非常罕见的,据认为发生在不到5%的病例中。一名69岁女性主诉入院前1个月腰痛伴右侧坐骨神经痛病史。腰椎的计算机断层扫描和磁共振成像显示一个哑铃状硬膜外肿块从L2延伸到L3,提示神经源性肿瘤。经椎旁入路和L2下半椎板部分切除术后,实现了肿瘤的完全切除,随后背部疼痛和放射性疼痛迅速改善。经组织病理学检查证实为伯基特淋巴瘤。全身PET-CT检查显示肠、肝、骨及左侧锁骨上淋巴结多灶性恶性病变。虽然Burkitt淋巴瘤是一种罕见的情况,但对于没有恶性病史的腰背部神经根性疼痛患者,应考虑其鉴别诊断。伯基特淋巴瘤可能是哑铃状脊柱肿瘤的病因。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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