Wrist Septic Arthritis: An 11 Year Review.

Robert Tze Jin Yap, Shian Chao Tay
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引用次数: 18

Abstract

Background: This report utilizes 11 years (2003-2013) of clinical records of patients for a retrospective evaluation of the effectiveness of various combinations of diagnostic methods, treatment options and surgical procedures to try to determine the optimal combinations to improve the rate of success for the treatment of septic wrist arthritis.

Methods: Analysis of records of 40 patients treated for septic wrist arthritis in our hospital involving records of physical examination, full blood analysis, biochemical, microbial profiles, type of surgical intervention, length of stay, number of surgical interventions to resolution and the rate of morbidity and mortality. The patients were subdivided into 2 groups, consisting of 6 (mortality) in one group and 34 (non-mortality) in the other. The various parameters as listed above were compared for differences. The patient records included those from immunocompromised elderly patients, with other existing medical complications such as gout, pseudogout, cellulitis and arthritic flare that made accurate diagnosis of septic wrist arthritis challenging.

Results: There is a trend showing better success in the treatment of septic wrist arthritis among patients without co-morbid medical problems. Due to the unavoidable delays in microbial identification, it was noted that escalation of antibiotics should be adopted especially for the immunocompromised patients.

Conclusions: Staphylococcus aureus, the most common microbial pathogen in our findings, point to the need to adopt a lower threshold for escalation of antibiotics for immunocompromised patients with slow reversal of infection in order to reduce morbidity, mortality, number of surgeries and length of post-operative stay.

手腕感染性关节炎:11年回顾。
背景:本报告利用11年(2003-2013)患者的临床记录,回顾性评价各种诊断方法、治疗方案和手术方式组合的有效性,试图确定最佳组合,以提高治疗化脓性手腕关节炎的成功率。方法:对我院收治的40例化脓性腕关节炎患者的体格检查、全血分析、生化、微生物谱、手术方式、住院时间、手术次数、发病率、死亡率等资料进行分析。将患者再分为两组,一组死亡率6例,另一组非死亡率34例。比较了上面列出的各种参数的差异。患者记录包括那些免疫功能低下的老年患者,以及其他现有的医学并发症,如痛风、假性痛风、蜂窝组织炎和关节炎爆发,这些都使得脓毒性手腕关节炎的准确诊断具有挑战性。结果:在没有合并症的患者中,有一种趋势显示脓毒性手腕关节炎的治疗成功率更高。由于微生物鉴定的不可避免的延误,需要注意的是,应采取抗生素的升级,特别是对免疫功能低下的患者。结论:金黄色葡萄球菌是我们研究中最常见的微生物病原体,这表明对于感染逆转缓慢的免疫功能低下患者,需要采用较低的抗生素升级阈值,以降低发病率、死亡率、手术次数和术后住院时间。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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