Nasal High-flow versus non-invasive ventilation in stable hypercapnic COPD: a preliminary report.

IF 2.3

Multidisciplinary Respiratory Medicine Pub Date : 2015-09-03 eCollection Date: 2015-01-01 DOI:10.1186/s40248-015-0019-y

Jens Bräunlich, Hans-Jürgen Seyfarth, Hubert Wirtz

引用次数: 72

Abstract

Background: There are no data available about effectiveness of Nasal High-flow (NHF)in chronic respiratory insufficiency.

Methods: Eleven COPD patients with stable hypercapnia were adjusted to NHF-system with a flow of 20 l/min. After six weeks patients were switched to non-invasive ventilation (NIV) for another six weeks period.

Results: NHF led to significant decreases in resting pCO2. Between the devices we found no differences in pCO2 levels.

Conclusions: NHF may thus be an alternative treatment device in stable hypercapnic COPD patients.

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稳定型高碳酸血症性COPD的鼻高流量与无创通气:初步报告。

背景:目前尚无关于鼻高流量(NHF)治疗慢性呼吸功能不全的有效性数据。方法:将11例COPD稳定期高碳酸血症患者调至流量为20l /min的nhf系统。六周后，患者切换到无创通气(NIV)再进行六周。结果:NHF使静息pCO2显著降低。在两种设备之间，我们没有发现二氧化碳分压水平的差异。结论:因此，NHF可能是稳定型高碳酸血症性COPD患者的一种替代治疗装置。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Multidisciplinary Respiratory Medicine Medicine-Pulmonary and Respiratory Medicine

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期刊介绍： Multidisciplinary Respiratory Medicine is the official journal of the Italian Respiratory Society - Società Italiana di Pneumologia (IRS/SIP). The journal publishes on all aspects of respiratory medicine and related fields, with a particular focus on interdisciplinary and translational research. The interdisciplinary nature of the journal provides a unique opportunity for researchers, clinicians and healthcare professionals across specialties to collaborate and exchange information. The journal provides a high visibility platform for the publication and dissemination of top quality original scientific articles, reviews and important position papers documenting clinical and experimental advances.