[A Sero-epidemiological Study on Transfusion-Transmissible Infectious among Volunteer Blood Donors From 2016 to 2020 in Nanjing].

Zhongguo shi yan xue ye xue za zhi Pub Date : 2022-10-01 DOI:10.19746/j.cnki.issn.1009-2137.2022.05.042

Tao Feng, Rui Zhu, Chun Zhou, Xiang-Ping Chen, Ni-Zhen Jiang, Shao-Wen Zhu

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Abstract

Objective: To investigate the status of transfusion-transmissible infection (TTI) among voluntary blood donors in Nanjing in recent five years, in order to provide data support for the recruitment of blood donors and formulation and updating of blood screening strategies.

Methods: HIV/HBV/HCV/TP serological markers were detected by ELISA in 487 120 blood donors in Nanjing from 2016 to 2020. Confirmatory assay was applied in anti-HIV positive samples by Nanjing Municipal Center for Disease Control and Prevention. The prevalence of TTI was calculated and the trend of disease was analyzed under different demographic groups.

Results: The total positive rate of TTI in blood donors was 0.49% (2 411/487 120), in which the overall seroprevalence rate of HBsAg, anti-HCV, anti-HIV and anti-TP was 0.23%, 0.09%, 0.01% and 0.16%, respectively. The overall prevalence of HIV and TP remained relatively steady (P>0.05), whereas HBV and HCV decreased year by year (P<0.05). The prevalence of TTI was higher among people with lower education level, high age group and first-time blood donation.

Conclusion: The prevalence of TTI among voluntary blood donors in Nanjing is at a low level from 2016 to 2020, but the risk still exists. The recruitment of regular donors and the improvement of blood screening technology can effectively reduce the risk of TTI.

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[2016 - 2020年南京市无偿献血者输血传播感染血清流行病学研究]。

目的:了解南京市自愿献血者近5年的输血传播感染(TTI)状况，为献血者的招募及血液筛查策略的制定和更新提供数据支持。方法:对2016 - 2020年南京市487 120例献血者进行HIV/HBV/HCV/TP血清学检测。对南京市疾病预防控制中心提供的hiv阳性标本采用验证性测定法。计算TTI的患病率，分析不同人群的发病趋势。结果:献血者TTI总阳性率为0.49%(2 411/487 120)，其中HBsAg、anti-HCV、anti-HIV和anti-TP总阳性率分别为0.23%、0.09%、0.01%和0.16%。HIV、TP总体患病率保持相对稳定(P>0.05)， HBV、HCV总体患病率呈逐年下降趋势(P结论:2016 - 2020年南京市献血者TTI患病率处于较低水平，但仍存在风险。招募定期献血者和改进血液筛查技术可以有效降低TTI的风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Zhongguo shi yan xue ye xue za zhi

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