Psychiatric Uses of Gabapentin.

Q3 Medicine
Innovations in clinical neuroscience Pub Date : 2022-07-01
Jon C Martin, Danielle Gainer
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引用次数: 0

Abstract

Objective: This article reviews evidence-based psychiatric uses of gabapentin, along with associated risks.

Method of research: An extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of gabapentin.

Results: Evidence supports gabapentin as a treatment for alcohol withdrawal and alcohol use disorder. There is sufficient evidence to consider gabapentin as a third-line treatment for social anxiety disorder and severe panic disorder. Evidence does not support the use of gabapentin for bipolar disorder, major depressive disorder (MDD), posttraumatic stress disorder (PTSD), obsessive compulsive disorder (OCD), stimulant use disorder, or opioid withdrawal. Risks of gabapentin use are highest among those with a history of a substance use disorder and those concurrently taking opioids.

Conclusion: While gabapentin has a place in psychiatry for a select few indications, the literature does not support its use for many studied diagnoses.

加巴喷丁的精神病学应用。
目的:本文综述了加巴喷丁的循证精神病学应用及其相关风险。研究方法:进行了广泛的文献综述,主要是PubMed中可搜索的文章,涉及加巴喷丁的精神病学用途、安全性和不良反应。结果:证据支持加巴喷丁治疗酒精戒断和酒精使用障碍。有足够的证据表明加巴喷丁可以作为治疗社交焦虑障碍和严重恐慌障碍的三线药物。证据不支持加巴喷丁用于双相情感障碍、重度抑郁症(MDD)、创伤后应激障碍(PTSD)、强迫症(OCD)、兴奋剂使用障碍或阿片类药物戒断。在有物质使用障碍史和同时服用阿片类药物的人群中,使用加巴喷丁的风险最高。结论:虽然加巴喷丁在精神病学中有少数适应症,但文献并不支持将其用于许多已研究的诊断。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Innovations in clinical neuroscience
Innovations in clinical neuroscience Medicine-Psychiatry and Mental Health
CiteScore
2.10
自引率
0.00%
发文量
87
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