[Ocular toxoplasmosis in infants 0 to 12 months of age with congenital toxoplasmosis].

Pub Date : 2022-06-01 DOI:10.4067/s0716-10182022000200265
Laura González V, Olivia Cardozo S, Margarita Samudio A, Mirta Mesquita R
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引用次数: 1

Abstract

Background: Ocular toxoplasmosis (OT) is a retinochoroiditis that evolves with several episodes of inflammation and can occur both in the congenital or acquired form of the disease, Aim: To describe the frequency and clinical characteristics of OT in infants aged 0 to 12 months, children of mothers with positive serology for toxoplasmosis in the perinatal period.

Methods: Cross-sectional descriptive, ambispective study.

Results: Infants from 0 to 12 months of age, whose mothers had positive serology for toxoplasmosis in the perinatal period, referred to the pediatric ophthalmology service for evaluation, were admitted. Demographic variables, maternal and infant serology and the results of the ophthalmological examination were collected. Data were analyzed in SPSS v21 Results: 46.4% of 125 infants had OT, of them 67.2% were female, (p = 0.04) the median age was 6 months, 41% had IgG and IgM positive. The lesions were bilateral in 82.8%, central in 86.2%, and inactive in 81%. Retinochoroiditis was accompanied by strabismus in 41%.

Conclusions: The frequency of OT in this population of infants with congenital toxoplasmosis was high. more than 80% of the eye lesions were inactive, centrally located and bilaterally involved.

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[0 ~ 12月龄婴儿先天性弓形虫病的眼弓形虫病]。
背景:眼弓形虫病(OT)是一种视网膜脉络膜炎,可发展为几次炎症发作,可发生在先天性或后天性疾病中。目的:描述0 - 12月龄婴儿,围产期弓形虫病血清学阳性母亲的孩子的OT的频率和临床特征。方法:横断面描述性、双视角研究。结果:0 ~ 12月龄的婴儿,其母亲在围产期弓形虫病血清学阳性,转至儿童眼科进行评估,入院。收集人口统计学变量、母婴血清学和眼科检查结果。结果125例患儿中46.4%为OT患儿,其中67.2%为女性,(p = 0.04)中位年龄为6个月,IgG和IgM阳性患儿占41%。双侧病变占82.8%,中心病变占86.2%,无活动性病变占81%。41%的视网膜脉络膜炎伴斜视。结论:先天性弓形虫病患儿OT发生率高。超过80%的眼部病变不活跃,位于中心,双侧受累。
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