Venous Outflow for Brain Arteriovenous Malformations: Overview and Treatment Implications.

International journal of neurobiology Pub Date : 2022-01-01 Epub Date: 2022-08-16
C Osorno-Cruz, Z Hasanpour, R Peart, W Dodd, D Laurent, S Aghili-Mehrizi, B Lucke-Wold, N Chalouhi
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Abstract

Introduction: Recent evidence has demonstrated a close relationship between the cerebral venous and lymphatic systems. Venous congestion has been implicated in a host of neurologic disorders, with relevance for vascular etiologies.

Objective: The authors aim to review the literature as it pertains to brain arteriovenous malformations' (BAVMs) venous hemodynamics and glymphatic pathways, as well as the implications of BAVM treatment.

Results: BAVMs offer a unique challenge, with sudden alteration in flow dynamics leading to increased hemorrhage risk and difficult challenges post-treatment.

Conclusion: Recent progress in the understanding of CNS fluid dynamics and glymphatic pathways have revealed important implications for BAVM pathology and treatment. As imaging techniques and treatment modalities advance, there is a need to further investigate this relationship as it relates to therapeutic options and post-treatment sequalae.

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脑动静脉畸形的静脉流出:概述和治疗意义。
导言:最新证据表明,脑静脉和淋巴系统之间存在密切关系。静脉充血与一系列神经系统疾病有关,与血管病因相关:作者旨在回顾与脑动静脉畸形(BAVMs)静脉血液动力学和淋巴管通路有关的文献,以及脑动静脉畸形治疗的意义:脑动静脉畸形是一项独特的挑战,其血流动力学的突然改变会导致出血风险增加,并给治疗后带来困难:结论:对中枢神经系统流体动力学和淋巴管通路的最新研究进展揭示了 BAVM 病理和治疗的重要意义。随着成像技术和治疗方式的进步,有必要进一步研究这种关系,因为它与治疗方案和治疗后遗症有关。
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