Review: Evidence-based Clinical Research of Anti-obesity Supplements in Japan.

Asuka Yasueda, Toshinori Ito, Kazuhisa Maeda
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引用次数: 7

Abstract

Background: The prevalence of obesity has increased dramatically throughout the world, and weight reduction through lifestyle management is urgently warranted. At present, numerous supplements advertised for their anti-overweight property are available in the Japanese market, but most of these lack proper evidence. Thus, we investigated dietary supplements that have been tested in clinical trials.

Search strategy: We researched anti-obesity supplements in the Japanese market using the google search engine in Japanese with the key terms "anti-obesity supplements," "diet supplements," and "weight reduction supplements."

Results: We listed 49 companies that supply anti-obesity supplements. Of these, 11 had published clinical evidence of the anti-obesity efficacy of their supplements. These products contain the following active ingredients: Angelica keiskei, bofu-tsusho-san, capsaishin, DHA/EPA, forskohlii, garcinia cambogia, lactoferrin, L-carnitine, oligonol, tea catechin, and yeast hydrolysate.

Conclusion: We obtained 11 supplements for which clinical evidence was published in medical journals in English. We also found 10 products for which clinical or animal evidence was published in Japanese. We expect that many companies will produce evidence of the efficacy of their products in the near future, thereby validating the use of dietary anti-obesity supplements in Japan.

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综述:日本抗肥胖补充剂的循证临床研究。
背景:肥胖的患病率在世界范围内急剧增加,通过生活方式管理减肥是迫切需要的。目前,日本市场上有许多宣传其抗超重特性的补品,但大多数都缺乏适当的证据。因此,我们研究了已经在临床试验中测试过的膳食补充剂。搜索策略:我们使用日语谷歌搜索引擎,以“抗肥胖补充剂”、“饮食补充剂”和“减肥补充剂”为关键词,研究了日本市场上的抗肥胖补充剂。结果:我们列出了49家提供抗肥胖补充剂的公司。其中,11家已经发表了临床证据,证明其补充剂具有抗肥胖功效。这些产品含有以下有效成分:当归、牛蒡、辣椒素、DHA/EPA、福斯柯利、藤黄果、乳铁蛋白、左旋肉碱、低聚醇、茶儿茶素和酵母水解物。结论:我们获得了11种临床证据发表在英文医学期刊上的补品。我们还发现有10种产品的临床或动物证据已用日文发表。我们预计,在不久的将来,许多公司将提供其产品功效的证据,从而验证在日本使用膳食抗肥胖补充剂。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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