[Role of the tissue antioxidant status in response to chronic irradiation of mice during early ontogenesis].

Abstract

The response of the liver and blood erythrocyte lipids to the low intensity chronic γ-irradiation action of mice at the dose of 8 cGy during early ontogenesis immediately and 7 months after irradiation is studied. The maintainance of the changed structural state of the lipid component in liver and especially blood erythrocytes which are characterized by a lower antioxidant status compared with the liver lipids is revealed during a long time after the cessation of irradiation. This confirms the possibility of using blood erythrocyte lipids as a perspective model for the estimation of the effects of the weak impact of unfavorable factors on the organism.