Individualized perfusion of sargent gloryvine decoction for clinical severe acute pancreatitis treatment.

Hepato-gastroenterology Pub Date : 2015-03-01
Ni Jun, Yuan Wenbin, Cen Feng, Yan Qiang, Zhang Guolei
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引用次数: 0

Abstract

Background/aims: To observe the effects of Sargent gloryvine decoction (SGD) on severe acute pancreatitis (SAP) treatment and to evaluate its clinical value.

Methodology: 112 patients of SAP in our hospital from January, 2005 to December, 2012 were recruited for retrospective analysis. They were divided into two groups, SGD group (62 patients) and control group without treated with SGD (50 patients). Inflammation factor, CT grade and Ranson grade were used to estimate the severity of SAP, and were compared in these two groups. In addition, peripancreatic infection, incidence of pseudo pancreatic cyst, time of anal exsufflation and duration of fever were used to evaluate the effect of SGD treatment. After perfusion of SGD for different time, hospitalization days and cost were recorded to evaluate clinical value of SGD.

Results: After perfusion, many indexes in SGD were remarkably superior to those of control group, such as duration of fever, incidence of pseudo pancreatic cyst, peripancreatic infection and Ranson grade. Meanwhile, SGD can sharply down-regulate inflammation reaction levels of SAP patients, so that the hospitalization days and costs can be obviously saved.

Conclusion: According to comparison, perfusion of SGD is a potential candidate for SAP treatment and is valuable in clinical application.

格洛藤汤个体化灌注治疗临床重症急性胰腺炎。
背景/目的:观察金缕藤汤(SGD)治疗重症急性胰腺炎(SAP)的疗效并评价其临床价值。方法:选取我院2005年1月至2012年12月收治的112例SAP患者进行回顾性分析。将患者分为SGD组(62例)和未使用SGD的对照组(50例)。采用炎症因子、CT分级和Ranson分级评估SAP的严重程度,并对两组患者进行比较。并以胰周感染、假性胰腺囊肿发生率、肛门排气时间、发热持续时间评价SGD治疗效果。记录SGD灌注不同时间后的住院天数和费用,评价SGD的临床价值。结果:灌注后,SGD患者发热时间、假性胰腺囊肿发生率、胰腺周围感染、Ranson分级等多项指标均明显优于对照组。同时,SGD能显著降低SAP患者的炎症反应水平,从而明显节省住院天数和费用。结论:经比较,SGD灌注治疗SAP是一种潜在的治疗方案,具有临床应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Hepato-gastroenterology
Hepato-gastroenterology 医学-外科
自引率
0.00%
发文量
1
审稿时长
1.9 months
期刊介绍: Hepato-Gastroenterology has been discontinued as of 2015. Extremely limited quantities of back issues in print available for sale.
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