Steven Thurber, Yasuhiro Kishi, Paula T Trzepacz, Jose G Franco, David J Meagher, Yanghyun Lee, Jeong-Lan Kim, Leticia M Furlanetto, Daniel Negreiros, Ming-Chyi Huang, Chun-Hsin Chen, Jacob Kean, Maeve Leonard
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引用次数: 18
Abstract
Principal components analysis applied to the Delirium Rating Scale-Revised-98 contributes to understanding the delirium construct. Using a multisite pooled international delirium database, the authors applied confirmatory factor analysis to Delirium Rating Scale-Revised-98 scores from 859 adult patients evaluated by delirium experts (delirium, N=516; nondelirium, N=343). Confirmatory factor analysis found all diagnostic features and core symptoms (cognitive, language, thought process, sleep-wake cycle, motor retardation), except motor agitation, loaded onto factor 1. Motor agitation loaded onto factor 2 with noncore symptoms (delusions, affective lability, and perceptual disturbances). Factor 1 loading supports delirium as a single construct, but when accompanied by psychosis, motor agitation's role may not be solely as a circadian activity indicator.
主成分分析应用于谵妄评定量表-修订-98有助于理解谵妄的结构。使用多站点汇集的国际谵妄数据库,作者对谵妄评定量表-修订-98的859名谵妄专家评估的成年患者进行了验证性因素分析(谵妄,N=516;nondelirium, N = 343)。验证性因子分析发现,除运动躁动外,所有诊断特征和核心症状(认知、语言、思维过程、睡眠-觉醒周期、运动迟缓)均加载到因子1上。运动躁动加载到因子2,伴有非核心症状(妄想、情感不稳定和知觉障碍)。因子1负荷支持谵妄作为一个单一的构念,但当伴有精神病时,运动躁动的作用可能不仅仅是作为一个昼夜活动指标。