Anti-thyroid peroxidase antibody in vitiligo: a prevalence study.

IF 1.7 Q4 ENDOCRINOLOGY & METABOLISM
Journal of Thyroid Research Pub Date : 2015-01-01 Epub Date: 2015-01-11 DOI:10.1155/2015/192736
R Dash, A Mohapatra, B S Manjunathswamy
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引用次数: 16

Abstract

Aim. The aim of the study was to study the relation of vitiligo with demographic data like age, sex, and duration and determine the prevalence of thyroid autoimmunity in vitiligo patients. Materials and Methods. This study was a cross sectional study consisting of 100 patients clinically diagnosed (old and new) as having vitiligo irrespective of age or sex. Patients with known thyroid disease on supplementation therapy, or who had undergone thyroid surgery, those on antithyroid medication, patients with other causes of leukoderma, and cases who do not provide informed consent were excluded from the study. Serum TSH and anti-TPO antibodies were measured in all the patients. Results. The prevalence of anti-TPO antibody positivity was found to be 28%. Conclusion. According to our study, none of our vitiligo patients had symptoms or signs of thyroid disease at the time of presentation but, on biochemical evaluation, anti-TPO antibodies were found in a considerable number of patients. Hence, we recommend screening of these patients with thyroid antibodies.

抗甲状腺过氧化物酶抗体在白癜风中的流行研究。
的目标。本研究的目的是研究白癜风与年龄、性别、病程等人口统计学数据的关系,并确定白癜风患者甲状腺自身免疫的患病率。材料与方法。这项研究是一项横断面研究,包括100名临床诊断为白癜风的患者(新老),无论年龄或性别。已知正在接受补充治疗的甲状腺疾病患者、接受过甲状腺手术的患者、接受抗甲状腺药物治疗的患者、其他原因的白癜风患者以及未提供知情同意的患者被排除在研究之外。检测患者血清TSH和抗tpo抗体。结果。抗tpo抗体阳性率为28%。结论。根据我们的研究,我们的白癜风患者在出现时都没有甲状腺疾病的症状或体征,但在生化评估中,在相当多的患者中发现了抗tpo抗体。因此,我们建议对这些患者进行甲状腺抗体筛查。
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来源期刊
Journal of Thyroid Research
Journal of Thyroid Research ENDOCRINOLOGY & METABOLISM-
CiteScore
4.40
自引率
0.00%
发文量
10
审稿时长
17 weeks
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