Lupus vulgaris: unusual presentation on face.

Q4 Medicine
Indian journal of leprosy Pub Date : 2014-04-01
A Pilani, R V Vora
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引用次数: 0

Abstract

Lupus vulgaris is a variant of cutaneous tuberculosis. As the disease has potential to mutilate when left untreated, leaving deforming scars and disfigurement, an early diagnosis is of paramount importance. Though the common type is plaque type, rarely mutilating and vegetative forms also are found. A 28 year old female, labourer presented with progressive annular plaque over right side of cheek extending upto right lower lid and ala of nose. There were two satellite plaques near the right side of giant lesion. On diascopy apple jelly nodule was seen. There was no regional lymhadenopathy. Histopathological examination showed many granulomas in upper dermis extending to deep dermis comprising of epitheloid cells with langhans' type of giant cells, lymphocytic infiltration & focal necrosis suggestive of lupus vulgaris. The consequences of failing to make an early diagnosis can be disastrous for the patients, as the progression of the disease can lead to necrosis, destruction of bones and cartilage leading to permanent deformity. Thus it is vital for clinicians to have a high index of suspicion of such atypical forms and take biopsy samples for histological and bacteriological studies.

寻常性狼疮:面部不寻常的表现。
寻常性狼疮是皮肤结核的一种变种。由于这种疾病在不治疗的情况下有可能致残,留下变形的疤痕和毁容,早期诊断是至关重要的。虽然常见的类型是斑块型,但也很少发现致残和营养形式。一名28岁女性劳工,表现为右脸颊渐进性环状斑块,延伸至右下眼睑和鼻翼。巨大病变右侧有两个卫星斑。软硬体上可见苹果果冻结节。无局部淋巴结病变。组织病理学检查显示真皮上层有大量肉芽肿,肉芽肿延伸至真皮深部,包括朗汉斯巨细胞型上皮细胞,淋巴细胞浸润及局灶性坏死,提示寻常性狼疮。未能及早诊断的后果对患者来说可能是灾难性的,因为疾病的进展可能导致坏死,骨骼和软骨的破坏,导致永久性畸形。因此,对于临床医生来说,高度怀疑这种非典型形式并采取活检样本进行组织学和细菌学研究是至关重要的。
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来源期刊
Indian journal of leprosy
Indian journal of leprosy Medicine-Dermatology
CiteScore
0.50
自引率
0.00%
发文量
0
期刊介绍: Indian Journal of Leprosy is one of the oldest journals of India published quarterly by Hind Kusht Nivaran Sangh (Indian Leprosy Association) since 1929. The Journal covers all research aspects of leprosy, tuberculosis and other mycobacterial diseases.
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