Midterm Results of David V Valve-Sparing Aortic Root Replacement in Acute Type A Aortic Dissection

IF 3.6 2区 医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Bradley G. Leshnower MD, Richard J. Myung MD, LaRonica McPherson RN, Edward P. Chen MD
{"title":"Midterm Results of David V Valve-Sparing Aortic Root Replacement in Acute Type A Aortic Dissection","authors":"Bradley G. Leshnower MD,&nbsp;Richard J. Myung MD,&nbsp;LaRonica McPherson RN,&nbsp;Edward P. Chen MD","doi":"10.1016/j.athoracsur.2014.08.079","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><p><span>The David V valve-sparing aortic root<span> replacement (David V) has been shown to provide excellent long-term valve function and low rates of valve-related complications in the elective treatment of aortic root aneurysms. The safety and durability of the David V in the repair of acute type A </span></span>aortic dissection (type A) are currently unclear. In this study, the midterm results of David V in the setting of type A aortic dissection were analyzed.</p></div><div><h3>Methods</h3><p>From 2005 to 2013, 350 patients underwent surgical repair of type A aortic dissection. Outcomes were analyzed in 43 consecutive patients who received a David V during repair of type A aortic dissection. Patients were followed with annual postoperative echocardiograms. Follow-up was 85% complete, with a mean duration of 40 ± 31 months.</p></div><div><h3>Results</h3><p><span>The mean age of these patients was 46 ± 10 years. There were two operative deaths (4.7%), and 93% of patients required a hemiarch replacement (n = 32) or a total arch replacement (n = 8) using hypothermic circulatory arrest. Cusp repairs were performed in 6 (14%) patients; 51% of patients had 3+ or greater preoperative aortic insufficiency (AI), 83% of patients left the operating room with zero AI, and the remainder had 1+ AI or less. No patient in the follow-up period developed </span>endocarditis<span> or required aortic valve replacement. At midterm follow-up, freedom from 2+ AI was 94%, and freedom from aortic valve replacement was 100%.</span></p></div><div><h3>Conclusions</h3><p>The David V can be performed with low morbidity and mortality in young patients presenting with type A aortic dissection who require aortic root replacement. At midterm follow-up, valve function is durable, and the incidence of valve-related complications is low.</p></div>","PeriodicalId":50976,"journal":{"name":"Annals of Thoracic Surgery","volume":"99 3","pages":"Pages 795-801"},"PeriodicalIF":3.6000,"publicationDate":"2015-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.athoracsur.2014.08.079","citationCount":"66","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Annals of Thoracic Surgery","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0003497514018268","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CARDIAC & CARDIOVASCULAR SYSTEMS","Score":null,"Total":0}
引用次数: 66

Abstract

Background

The David V valve-sparing aortic root replacement (David V) has been shown to provide excellent long-term valve function and low rates of valve-related complications in the elective treatment of aortic root aneurysms. The safety and durability of the David V in the repair of acute type A aortic dissection (type A) are currently unclear. In this study, the midterm results of David V in the setting of type A aortic dissection were analyzed.

Methods

From 2005 to 2013, 350 patients underwent surgical repair of type A aortic dissection. Outcomes were analyzed in 43 consecutive patients who received a David V during repair of type A aortic dissection. Patients were followed with annual postoperative echocardiograms. Follow-up was 85% complete, with a mean duration of 40 ± 31 months.

Results

The mean age of these patients was 46 ± 10 years. There were two operative deaths (4.7%), and 93% of patients required a hemiarch replacement (n = 32) or a total arch replacement (n = 8) using hypothermic circulatory arrest. Cusp repairs were performed in 6 (14%) patients; 51% of patients had 3+ or greater preoperative aortic insufficiency (AI), 83% of patients left the operating room with zero AI, and the remainder had 1+ AI or less. No patient in the follow-up period developed endocarditis or required aortic valve replacement. At midterm follow-up, freedom from 2+ AI was 94%, and freedom from aortic valve replacement was 100%.

Conclusions

The David V can be performed with low morbidity and mortality in young patients presenting with type A aortic dissection who require aortic root replacement. At midterm follow-up, valve function is durable, and the incidence of valve-related complications is low.

保留David V瓣主动脉根部置换术治疗急性A型主动脉夹层的中期结果
David V瓣保留主动脉根部置换术(David V瓣置换术)在选择性治疗主动脉根部动脉瘤中具有良好的长期瓣膜功能和较低的瓣膜相关并发症发生率。David V在急性A型主动脉夹层(A型)修复中的安全性和耐久性目前尚不清楚。在本研究中,我们分析了David V在A型主动脉夹层的中期结果。方法2005 ~ 2013年,350例A型主动脉夹层手术修复。结果分析了43例在a型主动脉夹层修复期间连续接受David V的患者。术后随访患者每年一次超声心动图。随访完成率85%,平均随访时间40±31个月。结果患者平均年龄46±10岁。有2例手术死亡(4.7%),93%的患者需要采用低温循环停搏进行血弓置换(n = 32)或全弓置换(n = 8)。6例(14%)患者进行尖部修复;51%的患者术前主动脉功能不全(AI)为3+或以上,83%的患者离开手术室时AI为零,其余患者AI为1+或以下。随访期间无患者发生心内膜炎或需要主动脉瓣置换术。中期随访时,2+ AI的自由度为94%,主动脉瓣置换术的自由度为100%。结论对于需要主动脉根置换术的年轻A型主动脉夹层患者,行David V手术的发病率和死亡率较低。在中期随访中,瓣膜功能持久,瓣膜相关并发症发生率低。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Annals of Thoracic Surgery
Annals of Thoracic Surgery 医学-呼吸系统
CiteScore
6.40
自引率
13.00%
发文量
1235
审稿时长
42 days
期刊介绍: The mission of The Annals of Thoracic Surgery is to promote scholarship in cardiothoracic surgery patient care, clinical practice, research, education, and policy. As the official journal of two of the largest American associations in its specialty, this leading monthly enjoys outstanding editorial leadership and maintains rigorous selection standards. The Annals of Thoracic Surgery features: • Full-length original articles on clinical advances, current surgical methods, and controversial topics and techniques • New Technology articles • Case reports • "How-to-do-it" features • Reviews of current literature • Supplements on symposia • Commentary pieces and correspondence • CME • Online-only case reports, "how-to-do-its", and images in cardiothoracic surgery. An authoritative, clinically oriented, comprehensive resource, The Annals of Thoracic Surgery is committed to providing a place for all thoracic surgeons to relate experiences which will help improve patient care.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信