Clinical queries addressed in patients with systemic autoimmune diseases. Can cardiovascular magnetic resonance give the final solution?

Inflammation & allergy drug targets Pub Date : 2014-01-01 DOI:10.2174/1871528113666141121155629

Sophie Mavrogeni, Georgia Karabela, Elias Gialafos, George Spiliotis, George Pentazos, Maria Mylona, Stelios Panopoulos, Sotirios Plastiras, Genovefa Kolovou, Efthymios Stavropoulos, Maria Boutsikou, George Kitas, Petros P Sfikakis

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引用次数: 2

Abstract

Objectives: To evaluate the potential of cardiovascular magnetic resonance (CMR) to answer queries, addressed in systemic autoimmune diseases (SAD).

Methods: Thirty-six patients aged 52±6 years, (range 27-71) with SAD and suspected cardiac disease underwent CMR by a 1.5 T, after routine evaluation, including clinical, ECG and echocardiographic examination. Steady-state, free precession cines, STIR T2-W and late gadolinium enhanced (LGE) images were evaluated.

Results: Abnormal findings were detected by: clinical evaluation in 14/36, ECG in 17/36, echocardiography in 11/36 and CMR in 30/36 SAD. Clinical, ECG and echocardiographic examination could not assess cardiac disease acuity and lesions'pathophysiology. In contrary, CMR identified cardiac lesions' etiology, acuity, need for catheterization and heart disease persistence, even if SAD was quiescent.

Conclusion: Clinical, ECG and echocardiographic abnormalities may suggest, but not always interpret cardiac involvement in SAD. CMR can help to identify both etiology and acuity of cardiac lesions and guide further diagnostic and/or therapeutic approach in these patients.

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系统性自身免疫性疾病患者的临床问题。心血管磁共振能给出最终的解决方案吗?

目的:评价心血管磁共振(CMR)在解决系统性自身免疫性疾病(SAD)问题中的潜力。方法:36例年龄(52±6岁)27 ~ 71岁的SAD合并疑似心脏病患者，经临床、心电图、超声检查等常规评估后，行1.5 T CMR。评估稳态、自由进动线、STIR T2-W和晚期钆增强(LGE)图像。结果:临床评价14/36，心电图17/36，超声心动图11/36,CMR 30/36 SAD检查异常。临床、心电图和超声检查不能评价心脏病变的急性程度和病变的病理生理。相反，即使SAD是静止的，CMR也能识别心脏病变的病因、敏锐度、导管插入术的需要和心脏病的持久性。结论:临床，心电图和超声心动图异常可能提示，但并不总是解释心脏累及SAD。CMR可以帮助确定心脏病变的病因和急性程度，并指导这些患者的进一步诊断和/或治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Inflammation & allergy drug targets

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