Abrus precatorius Leaves: Antioxidant Activity in Food and Biological Systems, pH, and Temperature Stability.

International Journal of Medicinal Chemistry Pub Date : 2014-01-01 Epub Date: 2014-01-30 DOI:10.1155/2014/748549
Vanitha Reddy Palvai, Sowmya Mahalingu, Asna Urooj
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引用次数: 20

Abstract

Natural antioxidants present in foods and other biological materials have attracted considerable interest because of their presumed safety and potential nutritional and therapeutic effects. Antioxidant constituents of plant materials act as radical scavengers and convert the radicals to less reactive species. Abrus precatorius (AP) was analyzed for its proximate and phytochemical composition. The leaves were extracted with methanol (ME) and analyzed for antioxidant activity by radical scavenging method, reducing power, ferric reducing capacity, and in vitro inhibition of Fenton's reagent-induced oxidation in oil emulsion and microsomes. In addition, the effect of temperature (100°C, 15, and 30 min) and pH (4.5, 7, and 9) C on the antioxidant activity of ME was investigated. The leaves were rich in total polyphenols, flavonoids, β-carotene, glutathione, α-tocopherol, and ascorbic acid. The ME exhibited varying degree of antioxidant activity in a dose-dependent manner. The AP exhibited more inhibition of oxidation in microsomes (73%) than compared to oil emulsion (21%). Heat treatment resulted in an increase of radical scavenging activity of extract (28% to 43%). At pH 4.5 the extract exhibited more antioxidant activity and stability compared to pH 7 and 9. Data indicates that potential exists for the utilization of Abrus precatorius as a natural antioxidant.

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鸡艾草叶片:食物和生物系统中的抗氧化活性、pH值和温度稳定性。
存在于食品和其他生物材料中的天然抗氧化剂由于其被假定的安全性和潜在的营养和治疗作用而引起了相当大的兴趣。植物材料的抗氧化成分作为自由基清除剂,并将自由基转化为活性较低的物种。对Abrus precatorius (AP)进行了近似值和植物化学成分分析。采用甲醇提取的方法,通过自由基清除能力、还原能力、铁还原能力、体外对Fenton试剂诱导的油乳和微粒体氧化的抑制作用等指标,分析其抗氧化活性。此外,还研究了温度(100°C、15和30 min)和pH(4.5、7和9)C对ME抗氧化活性的影响。叶片中含有丰富的总多酚、黄酮类化合物、β-胡萝卜素、谷胱甘肽、α-生育酚和抗坏血酸。ME表现出不同程度的抗氧化活性,并呈剂量依赖性。与油乳剂相比,AP对微粒体的氧化抑制作用更强(73%)。热处理使提取物的自由基清除活性增加(28% ~ 43%)。在pH为4.5时,与pH为7和9时相比,提取物具有更强的抗氧化活性和稳定性。数据表明,Abrus precatorius作为天然抗氧化剂具有开发利用的潜力。
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期刊介绍: International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis. International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis.
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