Comparative Analysis of the Antioxidant Activity of Cassia fistula Extracts.

International Journal of Medicinal Chemistry Pub Date : 2012-01-01 Epub Date: 2012-09-25 DOI:10.1155/2012/157125
Md Irshad, Md Zafaryab, Man Singh, M Moshahid A Rizvi
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Abstract

Antioxidant potential of various extracts of Cassia fistula was determined by the DPPH, FRAP, Fe(3+) reducing power, and hydrogen peroxide scavenging assay. Methanolic extracts of Cassia fistula showed the highest amount of phenolic and flavonoid content and reducing capacity, whereas hexane extracts exhibited the lowest level of reducing capacity. The order of antioxidant activity in Cassia fistula extracts displayed from higher to lower level as methanolic extracts of pulp, methanolic extracts of seed, hexane extracts of pulp, and hexane extracts of seed. The antioxidant potential of Cassia fistula extracts significantly correlated (P < 0.02) with the phenolic content of the methanolic extracts. Ascorbic acid taken as control showed highest antioxidant power in the present study.

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决明子提取物抗氧化活性的比较分析
通过 DPPH、FRAP、Fe(3+)还原力和过氧化氢清除试验测定了决明子各种提取物的抗氧化潜力。肉桂的甲醇提取物显示出最高的酚类和类黄酮含量以及还原能力,而正己烷提取物则显示出最低的还原能力。决明子提取物的抗氧化活性由高到低依次为果肉的甲醇提取物、种子的甲醇提取物、果肉的正己烷提取物和种子的正己烷提取物。决明子提取物的抗氧化潜力与甲醇提取物的酚含量有明显的相关性(P < 0.02)。在本研究中,以抗坏血酸作为对照的抗氧化能力最高。
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期刊介绍: International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis. International Journal of Medicinal Chemistry is a peer-reviewed, Open Access journal that publishes original research articles as well as review articles in all areas of chemistry associated with drug discovery, design, and synthesis.
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