Early trends in invasive pneumococcal disease in children following the introduction of 13-valent pneumococcal conjugate vaccine: results from eight years of active surveillance in a Mexican hospital.

Enrigue Chacon-Cruz, R M Rivas-Landeros, M L Volker-Soberanes
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引用次数: 16

Abstract

Background: In May 2012, universal vaccination with the 13-valent pneumococcal conjugate vaccine (PCV-13) was introduced for all children in the Tijuana region of Mexico, with a coverage of 80%.

Method: Between October 2005 and September 2013 active surveillance was undertaken for all invasive pneumococcal diseases (IPDs) in children admitted to the Tijuana General Hospital.

Results: Following PCV-13 implementation, there was a 75% reduction in overall IPD, and no cases of serotype 19A, pneumococcal meningitis, and pneumococcal-associated deaths.

Conclusions: These results are the first to show the effectiveness of PCV-13 in Mexico.

Abstract Image

引入13价肺炎球菌结合疫苗后儿童侵袭性肺炎球菌疾病的早期趋势:来自墨西哥一家医院8年主动监测的结果
背景:2012年5月,墨西哥蒂华纳地区的所有儿童开始普遍接种13价肺炎球菌结合疫苗(PCV-13),覆盖率为80%。方法:对2005年10月至2013年9月在蒂华纳总医院住院的所有儿童进行侵袭性肺炎球菌病(IPDs)的主动监测。结果:实施PCV-13后,总体IPD降低了75%,无血清型19A、肺炎球菌脑膜炎和肺炎球菌相关死亡病例。结论:这些结果首次显示了PCV-13在墨西哥的有效性。
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