Application of Positron Emission Tomography in Drug Development.

Abstract

Positron Emission Tomography (PET) is a clinically established noninvasive imaging modality. In PET, targeting ligands, or drug molecules labeled with a positron-emitting isotope, typically known as PET-radiopharmaceuticals, are introduced in to the body at a very low concentration (nanomolar or picomolar range), and are not intended to have any pharmacological effect.