[Postvaccinal fatal Streptococcus zooepidemicus necrotizing fasciitis in a young dog: a case report].

Tijdschrift Voor Diergeneeskunde Pub Date : 2014-09-01
S W M Greijdanus-Van Der Putten, J H Vos, J R V Duvekot, R Paillot, R McLean, H J Brokers, A E Heuvelink, N M Meertens, A S Waller
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引用次数: 0

Abstract

A 2.5-years-old female mongrel dog was routinely subcutaneously vaccinated. A few hours later mental dullness was noticed by the owner progressing into stupor the next day and resulting in a comatose state and death within 48 hours after vaccination. At post mortem examination, which was extended with histology and bacteriology, a necrotizing fasciitis and bacteremia caused by Streptococcus equi subsp. zooepidemicus were established. In the isolated Streptococcus strain four different superantigens were demonstrated that appeared to be able to produce exotoxins in vitro. Therefore, it is concluded that the minor skin trauma caused by vaccination enabled this strain to gain access to the subcutaneous tissue and to induce a necrotizing fasciitis. This process was complicated with a bacterial septicemia leading to death of the dog within 48 hours.

[接种后致死性动物流行性链球菌坏死性筋膜炎1例报告]。
一只2.5岁的雌性杂种狗常规皮下接种疫苗。几小时后,主人注意到精神迟钝,第二天进入昏迷状态,在接种疫苗后48小时内死亡。经组织和细菌学检查,尸检结果为马链球菌亚种引起的坏死性筋膜炎和菌血症。建立动物流行病。在分离的链球菌菌株中,证明了四种不同的超抗原似乎能够在体外产生外毒素。因此,结论是由疫苗接种引起的轻微皮肤创伤使该菌株能够进入皮下组织并诱导坏死性筋膜炎。这个过程很复杂,细菌败血症导致狗在48小时内死亡。
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来源期刊
Tijdschrift Voor Diergeneeskunde
Tijdschrift Voor Diergeneeskunde 农林科学-兽医学
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审稿时长
12-24 weeks
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