Effective interventions to improve medication adherence in Type 2 diabetes: a systematic review.

Joni L Strom Williams, Rebekah J Walker, Brittany L Smalls, Jennifer A Campbell, Leonard E Egede
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Abstract

Aim: Medication adherence is associated with improved outcomes in diabetes. Interventions have been established to help improve medication adherence; however, the most effective interventions in patients with Type 2 diabetes remain unclear. The goal of this study was to distinguish whether interventions were effective and identify areas for future research.

Methods: Medline was searched for articles published between January 2000 and May 2013, and a reproducible strategy was used. Study eligibility criteria included interventions measuring medication adherence in adults with Type 2 diabetes.

Results: Twenty seven studies met the inclusion criteria and 13 showed a statistically significant change in medication adherence.

Conclusion: Heterogeneity of the study designs and measures of adherence made it difficult to identify effective interventions that improved medication adherence. Additionally, medication adherence may not be solely responsible for achieving glycemic control. Researchers must emphasize tailored interventions that optimize management and improve outcomes, and examine the need for clear indicators of medication adherence.

Abstract Image

改善 2 型糖尿病患者服药依从性的有效干预措施:系统综述。
目的:坚持用药与糖尿病治疗效果的改善有关。目前已制定了一些干预措施来帮助提高用药依从性;但是,对 2 型糖尿病患者最有效的干预措施仍不明确。本研究的目的是区分干预措施是否有效,并确定未来研究的领域:方法:在 Medline 上检索了 2000 年 1 月至 2013 年 5 月间发表的文章,并采用了可重复的策略。研究资格标准包括对2型糖尿病成人患者的用药依从性进行干预:结果:27 项研究符合纳入标准,13 项研究显示用药依从性发生了统计学意义上的显著变化:结论:由于研究设计和衡量用药依从性的方法存在差异,因此很难确定能够改善用药依从性的有效干预措施。此外,用药依从性可能并不是实现血糖控制的唯一原因。研究人员必须强调量身定制的干预措施,以优化管理和改善疗效,并研究是否需要明确的用药依从性指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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