Cytohistopathological study of salivary gland lesions in bundelkhand region, uttar pradesh, India.

Pathology research international Pub Date : 2014-01-01 Epub Date: 2014-08-18 DOI:10.1155/2014/804265
Anita Omhare, Sanjeev Kumar Singh, Jitendra Singh Nigam, Ankit Sharma
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引用次数: 34

Abstract

Background. FNAC is a useful method for evaluating suspicious salivary glands lesions due to its low cost, minimum morbidity, rapid turnaround time, high specificity, and sensitivity. Aim. To know the frequency of the salivary gland lesions and cytohistological correlation in the Jhansi region, Uttar Pradesh, India. Material and Methods. In present study 124 cases were included and cytohistological correlation was made in 86 cases only. FNA was performed by using a 23/24-gauge needle without local anaesthesia. Air dried and 95% ethyl alcohol fixed wet smears were stained with Giemsa stain and Papanicolaou stain, respectively. Paraffin embedded tissue sections were stained with Haematoxylin and Eosin. Results. Parotid gland was the most commonly involved salivary gland. The commonest age group was 20 to 29 years, 30 to 39 years, and 60 to 69 years for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. The overall male to female ratio was 1.17 : 1. The diagnostic accuracy of FNAC was 100%, 93.3%, and 88.2% for nonneoplastic lesions, benign tumours, and malignant tumours, respectively. Conclusion. The high accuracy, sensitivity, and specificity of FNAC confirm that preoperative cytology is a useful, quick, reliable diagnostic technique for rapid diagnosis and suitable for developing countries.

Abstract Image

Abstract Image

印度北方邦本德尔坎德邦地区唾液腺病变的细胞组织病理学研究。
背景。FNAC具有成本低、发病率低、周期短、特异性高、灵敏度高等优点,是评估可疑唾液腺病变的有效方法。的目标。了解印度北方邦Jhansi地区唾液腺病变的频率和细胞组织学相关性。材料和方法。本研究纳入124例,仅86例进行了细胞组织学相关分析。FNA采用23/24号针,局部不麻醉。风干片和95%乙醇固定湿片分别用吉姆萨染色法和帕帕尼科劳染色法进行染色。石蜡包埋组织切片用苏木精和伊红染色。结果。腮腺是最常受累的唾液腺。非肿瘤性病变、良性肿瘤和恶性肿瘤最常见的年龄组分别为20 ~ 29岁、30 ~ 39岁和60 ~ 69岁。总体男女比例为1.17:1。FNAC对非肿瘤性病变、良性肿瘤和恶性肿瘤的诊断准确率分别为100%、93.3%和88.2%。结论。FNAC的高准确性、敏感性和特异性证实了术前细胞学是一种有用、快速、可靠的快速诊断技术,适用于发展中国家。
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