Serum calcium level is associated with brachial-ankle pulse wave velocity in middle-aged and elderly Chinese.

Biomedical and environmental sciences : BES Pub Date : 2014-08-01 DOI:10.3967/bes2014.091

Xin Ru Deng, Yin Fei Zhang, Tian Ge Wang, Bai Hui Xu, Ji Chao Sun, Lie Bin Zhao, Min Xu, Yu Hong Chen, Wei Qing Wang, Yu Fang Bi, Jie Li Lu

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引用次数: 9

Abstract

Objective: To study the relation between serum calcium level and elevated BaPWV in Chinese subjects.

Methods: The relation between serum calcium level and elevated BaPWV was studied in 9 615 subjects. The mean value of left and right BaPWV was analyzed. BaPWV was defined as high when it was ⋝1752.5 cm/s (the upper quartile) either side.

Results: The BaPWV and its elevated percentage progressively increased across the quartiles of the serum calcium level (P<0.05). The prevalence of elevated BaPWV was significantly higher in subjects of the second, third and highest quartiles than in those of the lowest quartile (26.9%, 28.4%, and 33.2% vs 23.7%, P=0.0116, P=0.0004, and P<0.0001). Logistic regression analysis revealed that the risk of elevated BaPWV was 1.32- fold higher in subjects of the highest quartile than in those of the lowest quartile (OR=1.32, 95% CI: 1.08-1.60).

Conclusion: The elevated serum calcium level is related to an elevated BaPWV and a higher risk of arterial stiffness, independent of conventional risk factors, in middle-aged and elderly Chinese subjects.

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中国中老年人群血钙水平与肱-踝脉波速度的关系。

目的:探讨中国人群血钙水平与BaPWV升高的关系。方法:对9615例患者血清钙水平与BaPWV升高的关系进行分析。分析左、右BaPWV的平均值。当BaPWV两侧为⋝1752.5 cm/s(上四分位数)时，BaPWV被定义为高。结果:在血清钙水平的各个四分位数中，BaPWV及其升高百分比逐渐增加(结论:在中国中老年受试者中，血清钙水平升高与BaPWV升高和动脉僵硬风险升高有关，独立于常规危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Biomedical and environmental sciences : BES

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