Acne vulgaris: an inflammatory disease even before the onset of clinical lesions.

Marco Alexandre Rocha, Caroline Sousa Costa, Edileia Bagatin
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引用次数: 44

Abstract

Acne is a chronic self-limited disease, which affects mostly teenagers, without gender difference. In recent years, the incidence has increased in female adults. The factors involved in this epidemiological observation are still under discussion in the literature. Clinically, acne is characterized by different types of lesions. The disease affects the regions rich in sebaceous glands (face, chest and upper back). The clinical lesions are: open and closed comedones, erythematous papules, pustules, nodules and different types of scars. Taking into consideration the general concept of inflammation (redness, pain, heat and loss of function), acne is traditionally classified as non-inflammatory (open and closed comedones) and inflammatory (other primary lesions). With the knowledge advancement this concept seems to be wrong and therefore acne would be an inflammatory disease even before the onset of their clinical lesions.

寻常痤疮:一种炎症性疾病,甚至在发病前就有临床病变。
痤疮是一种慢性自限性疾病,以青少年为主,无性别差异。近年来,成年女性的发病率有所上升。有关这一流行病学观察的因素在文献中仍在讨论中。临床上,痤疮的特点是不同类型的病变。该病影响皮脂腺丰富的区域(面部、胸部和上背部)。临床病变有:开闭性粉刺、红斑丘疹、脓疱、结节及不同类型的疤痕。考虑到炎症的一般概念(发红、疼痛、发热和功能丧失),痤疮传统上分为非炎症性(开闭性)和炎症性(其他原发性病变)。随着知识的进步,这个概念似乎是错误的,因此痤疮将是一种炎症性疾病,甚至在他们的临床病变发作之前。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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