Pattern of Renal Diseases among Children in The Niger Delta Region, Nigeria.

G I McGil Ugwu, G Nwajei, U Chinemelu
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Abstract

Introduction: Childhood renal diseases are increasing in Nigeria. It is necessary to monitor the nature of these diseases in each locality for effective health care planning. Our aim was to document the nature of renal diseases in the Niger Delta Region of Nigeria and compare it with other regions in the country.

Methods: We reviewed the documents of all children presenting with renal diseases between January 2010 and December 2012 to the Delta State University Teaching Hospital in Oghara and GN Children's Clinic in Warri, the two major pediatric nephrology service providers in the Niger Delta region of Nigeria.

Results: A total of 110 patients were studied, comprising 73 males and 37 females. About half the patients were aged 5-10 years. Renal diseases accounted for 1.6% of all admissions during the same period. The commonest presentations were nephrotic syndrome (30%), acute glomerulonephritis (18.2%), urinary tract infection (16.3%), acute kidney injury (10.9%), chronic kidney diseases (7.3%) and obstructive uropathy (7.3%). Regarding the outcome of renal diseases, 80% of the patients achieved full recovery, 14.6% died and 5.4% were discharged against medical advice or lost to follow up. The highest mortality rate was among patients with chronic kidney disease (75%), followed by acute kidney injury (41.7%).

Conclusion: A renal registry based on unified definitions of renal diseases is required for the proper planning of health care strategies. Mortality rate of chronic kidney disease was high in this study mostly due to late presentation.

尼日利亚尼日尔三角洲地区儿童肾脏疾病的模式。
儿童肾脏疾病在尼日利亚呈上升趋势。有必要在每个地方监测这些疾病的性质,以便进行有效的卫生保健规划。我们的目的是记录尼日利亚尼日尔三角洲地区肾脏疾病的性质,并将其与该国其他地区进行比较。方法:我们回顾了2010年1月至2012年12月期间在尼日利亚尼日尔三角洲地区两家主要儿科肾脏病服务机构——奥哈拉三角洲州立大学教学医院和瓦里GN儿童诊所就诊的所有肾脏疾病患儿的资料。结果:共纳入110例患者,其中男性73例,女性37例。大约一半的患者年龄在5-10岁之间。同期,肾脏疾病占所有入院患者的1.6%。最常见的表现是肾病综合征(30%)、急性肾小球肾炎(18.2%)、尿路感染(16.3%)、急性肾损伤(10.9%)、慢性肾病(7.3%)和梗阻性尿病(7.3%)。肾脏疾病转归方面,80%的患者完全康复,14.6%的患者死亡,5.4%的患者不遵医嘱出院或失访。死亡率最高的是慢性肾脏疾病(75%),其次是急性肾损伤(41.7%)。结论:在肾脏疾病统一定义的基础上,需要肾脏登记,以适当规划卫生保健策略。在本研究中,慢性肾脏疾病的死亡率很高,主要是由于出现较晚。
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